iPTMnet Report for P12270 (TPR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12270 / TPR_HUMAN
Protein Name Nucleoprotein TPR
Gene Name Name: TPR
Organism Homo sapiens (Human)

PRO ID PR:P12270
DAG View
PRO Name nucleoprotein TPR (human)
Definition A nucleoprotein TPR that is encoded in the genome of human.
Short Label hTPR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12270 (TPR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
K27 Ubiquitination PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
R105 Methylation PhosphoSitePlus
S111 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
K117 Methylation PhosphoSitePlus
K124 Methylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K252 Acetylation PhosphoSitePlus   UniProt 19608861
K252 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K262 Acetylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K312 Acetylation PhosphoSitePlus   UniProt 19608861
K312 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K345 Acetylation PhosphoSitePlus   UniProt 19608861
K351 Ubiquitination PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S379 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
T381 Phosphorylation PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K428 Acetylation PhosphoSitePlus   UniProt 19608861
K428 Ubiquitination PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K449 Acetylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K457 Acetylation PhosphoSitePlus   UniProt 19608861
K463 Ubiquitination PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K477 Acetylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus   UniProt 24275569
S523 Phosphorylation PhosphoSitePlus   UniProt 24275569
S527 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
T588 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus   UniProt 24275569
S637 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
T641 Phosphorylation PhosphoSitePlus
S646 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T647 Phosphorylation PhosphoSitePlus
S648 Phosphorylation phospho.ELM 18669648
T650 O-Glycosylation GlyGen 31373491
T650 Phosphorylation PhosphoSitePlus
S652 O-Glycosylation GlyGen 31373491
S652 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T653 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K669 Ubiquitination PhosphoSitePlus
K673 Ubiquitination PhosphoSitePlus
Y682 Phosphorylation PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus
R708 Methylation PhosphoSitePlus
K713 Acetylation PhosphoSitePlus   UniProt 19608861
K713 Ubiquitination PhosphoSitePlus
K723 Acetylation PhosphoSitePlus   UniProt 19608861
K723 Ubiquitination PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus
T740 Phosphorylation PhosphoSitePlus
K748 Acetylation PhosphoSitePlus   UniProt 19608861
T750 Phosphorylation PhosphoSitePlus
T753 Phosphorylation PhosphoSitePlus
K755 Acetylation PhosphoSitePlus   UniProt 19608861
K755 Ubiquitination PhosphoSitePlus
T764 Phosphorylation PhosphoSitePlus
R768 Methylation PhosphoSitePlus
K773 Ubiquitination PhosphoSitePlus
K792 Acetylation PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus
S849 Phosphorylation IEDB 35494241
K854 Acetylation PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
K895 Ubiquitination PhosphoSitePlus
K899 Ubiquitination PhosphoSitePlus
K905 Ubiquitination PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
S920 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T923 Phosphorylation PhosphoSitePlus
K925 Acetylation PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
K952 Ubiquitination PhosphoSitePlus
K956 Ubiquitination PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
K978 Ubiquitination PhosphoSitePlus
K995 Ubiquitination PhosphoSitePlus
K1038 Ubiquitination PhosphoSitePlus
K1081 Ubiquitination PhosphoSitePlus
K1100 Ubiquitination PhosphoSitePlus
K1105 Methylation PhosphoSitePlus
K1105 Ubiquitination PhosphoSitePlus
K1119 Ubiquitination PhosphoSitePlus
S1122 Phosphorylation PhosphoSitePlus
K1128 Ubiquitination PhosphoSitePlus
K1144 Ubiquitination PhosphoSitePlus
K1165 Ubiquitination PhosphoSitePlus
K1169 Ubiquitination PhosphoSitePlus
S1173 Phosphorylation PhosphoSitePlus
S1185 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 17287340, 19690332, 20068231
S1187 Phosphorylation PhosphoSitePlus
K1191 Ubiquitination PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus
S1241 Phosphorylation PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
K1254 Ubiquitination PhosphoSitePlus
T1255 Phosphorylation PhosphoSitePlus
K1265 Acetylation PhosphoSitePlus
K1265 Methylation PhosphoSitePlus
T1266 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T1268 Phosphorylation PhosphoSitePlus
T1275 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
K1277 Acetylation PhosphoSitePlus
K1296 Ubiquitination PhosphoSitePlus
K1299 Ubiquitination PhosphoSitePlus
K1317 Acetylation PhosphoSitePlus
S1318 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
K1325 Acetylation PhosphoSitePlus
K1326 Acetylation PhosphoSitePlus
K1326 Methylation PhosphoSitePlus
K1347 Ubiquitination PhosphoSitePlus
S1385 Phosphorylation PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
K1400 Ubiquitination PhosphoSitePlus
K1420 Ubiquitination PhosphoSitePlus
K1427 Acetylation PhosphoSitePlus
K1427 Ubiquitination PhosphoSitePlus
K1429 Ubiquitination PhosphoSitePlus
Y1441 Phosphorylation PhosphoSitePlus
Y1445 Phosphorylation PhosphoSitePlus
K1449 Ubiquitination PhosphoSitePlus
T1458 Phosphorylation PhosphoSitePlus
S1459 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1462 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1463 Phosphorylation PhosphoSitePlus
K1480 Ubiquitination PhosphoSitePlus
S1490 Phosphorylation PhosphoSitePlus
K1491 Ubiquitination PhosphoSitePlus
S1492 Phosphorylation PhosphoSitePlus
S1495 Phosphorylation PhosphoSitePlus
K1502 Ubiquitination PhosphoSitePlus
T1503 Phosphorylation PhosphoSitePlus
S1505 Phosphorylation PhosphoSitePlus
K1507 Ubiquitination PhosphoSitePlus
R1535 Methylation PhosphoSitePlus
K1549 Acetylation PhosphoSitePlus
K1552 Acetylation PhosphoSitePlus
K1563 Ubiquitination PhosphoSitePlus
K1571 Acetylation PhosphoSitePlus
K1571 Ubiquitination PhosphoSitePlus
T1600 Phosphorylation PhosphoSitePlus
K1603 Methylation PhosphoSitePlus
K1603 Ubiquitination PhosphoSitePlus
S1611 Phosphorylation PhosphoSitePlus
K1637 Ubiquitination PhosphoSitePlus
K1648 Ubiquitination PhosphoSitePlus
T1650 Phosphorylation PhosphoSitePlus
S1653 Phosphorylation PhosphoSitePlus
R1656 Methylation PhosphoSitePlus
S1660 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S1660 Phosphorylation PhosphoSitePlus
T1661 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S1662 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S1662 Phosphorylation PhosphoSitePlus
T1666 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T1666 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1670 Acetylation PhosphoSitePlus
K1670 Ubiquitination PhosphoSitePlus
T1672 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T1672 Phosphorylation PhosphoSitePlus
S1676 O-Glycosylation GlyGen   PhosphoSitePlus 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S1676 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18847512
S1676 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T1677 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T1677 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18847512
T1677 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S1679 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S1679 Phosphorylation PhosphoSitePlus 18847512
S1679 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T1682 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T1682 Phosphorylation PhosphoSitePlus
K1690 Ubiquitination PhosphoSitePlus
S1691 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S1691 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1692 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T1712 Phosphorylation PhosphoSitePlus
S1804 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T1822 Phosphorylation PhosphoSitePlus
T1831 Phosphorylation PhosphoSitePlus
S1838 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1839 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1847 Phosphorylation PhosphoSitePlus
T1850 Phosphorylation PhosphoSitePlus
K1857 Acetylation PhosphoSitePlus
S1890 Phosphorylation PhosphoSitePlus
S1893 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1903 Phosphorylation PhosphoSitePlus
S2034 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2037 Phosphorylation PhosphoSitePlus   UniProt 23186163
T2042 Phosphorylation PhosphoSitePlus
S2047 Phosphorylation PhosphoSitePlus
S2048 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S2050 Phosphorylation PhosphoSitePlus   UniProt 17525332, 23186163, 19690332
S2054 Phosphorylation PhosphoSitePlus
S2060 O-Glycosylation GlyGen 31373491
S2061 O-Glycosylation GlyGen 31373491
S2063 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S2073 Phosphorylation PhosphoSitePlus   UniProt 21406692, 17081983, 24938596
S2073 Phosphorylation P06493 (CDK1) PhosphoSitePlus 24938596
R2106 Methylation PhosphoSitePlus
S2108 Phosphorylation PhosphoSitePlus 24938596
S2108 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 24938596
R2111 Methylation PhosphoSitePlus   UniProt 24129315
T2116 Phosphorylation neXtProt   PhosphoSitePlus   Signor 22028470, 18794356, 12594221
T2116 Phosphorylation P28482 (MAPK1) neXtProt   Signor 22028470, 18794356, 12594221
R2132 Methylation PhosphoSitePlus
T2133 Phosphorylation PhosphoSitePlus
S2136 Phosphorylation PhosphoSitePlus
T2137 Phosphorylation neXtProt   PhosphoSitePlus   Signor   UniProt 22028470, 23186163, 18794356, ...12594221
T2137 Phosphorylation P28482 (MAPK1) neXtProt   Signor 22028470, 18794356, 12594221
T2139 Phosphorylation PhosphoSitePlus
T2146 Phosphorylation PhosphoSitePlus
S2155 Phosphorylation neXtProt   PhosphoSitePlus   Signor   UniProt 22028470, 23186163, 12594221, ...18220336, 18794356, 18669648, 24275569, 19690332, 20068231, 17924679
S2155 Phosphorylation P28482 (MAPK1) neXtProt   Signor 22028470, 18794356, 12594221
R2163 Methylation PhosphoSitePlus
R2165 Methylation PhosphoSitePlus
S2176 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S2178 Phosphorylation PhosphoSitePlus
S2180 Phosphorylation PhosphoSitePlus
S2187 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
S2187 Phosphorylation PhosphoSitePlus
Y2194 Phosphorylation PhosphoSitePlus
S2210 Phosphorylation PhosphoSitePlus
T2214 Phosphorylation PhosphoSitePlus   Signor 18794356
T2214 Phosphorylation P28482 (MAPK1) Signor 18794356
R2327 Methylation PhosphoSitePlus
T2330 O-Glycosylation GlyGen 31492838, 33465208, 35289036, ...29351928, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 28657654, 27655845, 33214551, 30379171, 30059200, 25367160, 35254053, 34019948, 36240223, 28510447, 20068230
T2331 O-Glycosylation GlyGen 31373491
R2333 Methylation PhosphoSitePlus
R2337 Methylation PhosphoSitePlus
R2339 Methylation PhosphoSitePlus
R2343 Methylation PhosphoSitePlus
R2345 Methylation PhosphoSitePlus
R2354 Methylation PhosphoSitePlus
R2359 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S62 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD 20068231
S270 Phosphorylation HPRD 20068231
S379 Phosphorylation HPRD 19413330, 19664995, 18452278, ...18669648, 19415658, 20068231
T381 Phosphorylation HPRD 19413330, 17081983
S522 Phosphorylation HPRD 18691976
S523 Phosphorylation HPRD 17081983
S527 Phosphorylation HPRD 17081983
S528 Phosphorylation HPRD 17081983
S529 Phosphorylation HPRD 17081983
S530 Phosphorylation HPRD 17081983
T641 Phosphorylation HPRD 20068231
S646 Phosphorylation HPRD 17287340, 20068231
T647 Phosphorylation HPRD 20068231
S648 Phosphorylation HPRD 18669648, 20068231
T650 Phosphorylation HPRD 17081983, 20068231, 18452278
S652 Phosphorylation HPRD 18669648, 20068231
T653 Phosphorylation HPRD 18669648, 20068231
T663 Phosphorylation HPRD 20068231
T740 Phosphorylation HPRD 20068231
S920 Phosphorylation HPRD 17525332
S1185 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20058876, 20068231, 19691289
T1252 Phosphorylation HPRD 20068231
T1255 Phosphorylation HPRD 20068231
S1385 Phosphorylation HPRD 20068231
T1390 Phosphorylation HPRD 20068231
S1398 Phosphorylation HPRD 20068231
T1458 Phosphorylation HPRD 20068231
S1459 Phosphorylation HPRD 18669648, 20068231
S1462 Phosphorylation HPRD 18669648, 20068231
T1666 Phosphorylation HPRD 18669648
S1676 Phosphorylation HPRD 18669648, 20068231
T1677 Phosphorylation HPRD 19413330, 18669648
S1691 Phosphorylation HPRD 18669648, 20068231
T1692 Phosphorylation HPRD 20068231
S1725 Phosphorylation HPRD 19007248
S1804 Phosphorylation HPRD 19007248
S1838 Phosphorylation HPRD 18669648, 20068231, 18452278
T1839 Phosphorylation HPRD 18669648, 20068231
S1847 Phosphorylation HPRD 18452278
S2034 Phosphorylation HPRD 17525332, 18077418
S2037 Phosphorylation HPRD 15302935, 18452278
S2047 Phosphorylation HPRD 18077418
S2048 Phosphorylation HPRD 18669648, 19691289, 20068231, ...18452278
S2050 Phosphorylation HPRD 18077418, 17525332, 19691289, ...18452278
S2054 Phosphorylation HPRD 18452278
S2073 Phosphorylation HPRD 17081983, 20068231
S2155 Phosphorylation HPRD 17081983, 17287340, 18212344, ...18767875, 18452278, 19651622, 18669648, 18707149, 19415658, 20068231, 17924679
T2175 Phosphorylation HPRD 18452278
S2178 Phosphorylation HPRD 18452278
S2180 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R105 P105 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R105 C105 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S135 F135 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K177 R177 Biomuta DOID:263 / kidney cancer [ cosmic ]
K204 N204 Biomuta DOID:3571 / liver cancer [ cosmic ]
K335 T335 Biomuta DOID:1324 / lung cancer [ cosmic ]
K351 R351 Biomuta DOID:3571 / liver cancer [ cosmic ]
S361 F361 Biomuta DOID:1612 / breast cancer [ cosmic ]
S371 C371 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K387 N387 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K413 E413 Biomuta DOID:1319 / brain cancer [ icgc ]
K421 N421 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K433 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S530 F530 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T572 I572 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K575 T575 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K582 T582 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S632 N632 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S637 F637 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S640 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T647 A647 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S648 L648 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T650 I650 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S652 F652 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K673 T673 Biomuta DOID:363 / uterine cancer [ icgc ]
K673 * Biomuta DOID:263 / kidney cancer [ cosmic ]
K691 I691 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R708 Q708 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R708 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T740 I740 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R768 K768 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R768 T768 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K877 R877 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K877 N877 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
K877 E877 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S919 C919 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S929 G929 Biomuta DOID:3571 / liver cancer [ cosmic ]
K956 R956 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S960 R960 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S960 N960 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K1169 T1169 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1169 M1169 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1192 C1192 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1192 F1192 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1192 Y1192 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1241 G1241 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1252 I1252 Biomuta DOID:1612 / breast cancer [ icgc ]
T1275 N1275 Biomuta DOID:1612 / breast cancer [ icgc ]
K1317 N1317 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1390 S1390 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1429 I1429 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1459 L1459 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1490 T1490 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S1490 * Biomuta DOID:184 / bone cancer [ cosmic ]
K1502 N1502 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1505 C1505 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
R1535 T1535 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1549 N1549 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1637 M1637 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T1682 I1682 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1804 L1804 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K1857 T1857 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1893 F1893 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2047 T2047 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2048 Y2048 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2050 F2050 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2060 P2060 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2073 L2073 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S2108 Y2108 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R2111 C2111 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T2146 I2146 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2155 L2155 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R2165 Q2165 Biomuta DOID:263 / kidney cancer [ icgc ]
R2337 H2337 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
R2337 C2337 Biomuta DOID:4159 / skin cancer [ cosmic ]
R2339 C2339 Biomuta DOID:9256 / colorectal cancer [ cosmic ]