iPTMnet Report for P12236 (SLC25A6)
Protein Information
UniProt AC / UniProt ID | P12236 / ADT3_HUMAN |
Protein Name | ADP/ATP translocase 3 |
Gene Name | Name: SLC25A6 Synonyms:ANT3;ORFNames:CDABP0051; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P12236 |
PRO Name | ADP/ATP translocase 3 (human) |
Definition | An ADP/ATP translocase 3 that is encoded in the genome of human. |
Short Label | hSLC25A6 |
Category | organism-gene |
P12236 (SLC25A6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22223895 | ||
T2 | Acetylation | score1 | UniProt | 19413330, 22223895, 25944712 | ||
K10 | Acetylation | score1 | PhosphoSitePlus | |||
K10 | Methylation | score1 | PhosphoSitePlus | |||
K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
K23 | Acetylation | score1 | PhosphoSitePlus | |||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
T24 | Phosphorylation | score1 | PhosphoSitePlus | |||
K33 | Acetylation | score1 | PhosphoSitePlus | |||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
K43 | Acetylation | score1 | PhosphoSitePlus | |||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
K49 | Methylation | score1 | PhosphoSitePlus | |||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y51 | Phosphorylation | score1 | PhosphoSitePlus | |||
K52 | Methylation | score1 | PhosphoSitePlus | |||
K63 | Acetylation | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
T84 | Phosphorylation | score1 | PhosphoSitePlus | |||
K92 | Acetylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K94 | Acetylation | score1 | PhosphoSitePlus | |||
K96 | Acetylation | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
K105 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y112 | Phosphorylation | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
T139 | Phosphorylation | score1 | PhosphoSitePlus | |||
R140 | Methylation | score1 | PhosphoSitePlus | |||
K147 | Acetylation | score1 | PhosphoSitePlus | |||
K147 | Methylation | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976 | ||
T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
R155 | Methylation | score1 | PhosphoSitePlus | |||
C160 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
K163 | Acetylation | score1 | PhosphoSitePlus | |||
K163 | Ubiquitination | score1 | PhosphoSitePlus | |||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y191 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
K199 | Sumoylation | score1 | PhosphoSitePlus | |||
K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Sumoylation | score1 | PhosphoSitePlus | |||
Y229 | Phosphorylation | score1 | PhosphoSitePlus | |||
S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
K268 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
K272 | Acetylation | score1 | PhosphoSitePlus | |||
K272 | Methylation | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
S276 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P49841 (GSK3B) | S9 | P12236 (SLC25A6) | unknown | eFIP | 28591721 | |
Phosphorylation | Q9WV60 (Gsk3b) | S9 | P12236 (SLC25A6) | increased_association | eFIP | 28591721 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T24 | K24 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S148 | * | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic, icgc ] | |
R155 | L155 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
T197 | M197 | Biomuta | DOID:3371 / chondrosarcoma [ cosmic ] | |
K268 | R268 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc, tcga ] |