Protein Information

Cytoscape View


UniProt AC / UniProt ID P12236 / ADT3_HUMAN
Protein Name ADP/ATP translocase 3
Gene Name Name: SLC25A6
Synonyms:ANT3;ORFNames:CDABP0051;
Organism Homo sapiens (Human)

PRO ID PR:P12236
DAG View
PRO Name ADP/ATP translocase 3 (human)
Definition An ADP/ATP translocase 3 that is encoded in the genome of human.
Short Label hSLC25A6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12236 (SLC25A6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22223895
T2 Acetylation UniProt 19413330, 22223895, 25944712
K10 Acetylation PhosphoSitePlus
K10 Methylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
K43 Acetylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K49 Methylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
K52 Methylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
T84 Phosphorylation PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K94 Acetylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K105 Acetylation PhosphoSitePlus   UniProt 19608861
K105 Ubiquitination PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
R140 Methylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
K147 Methylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S148 Phosphorylation HPRD   PhosphoSitePlus 18691976
T150 Phosphorylation PhosphoSitePlus
R155 Methylation PhosphoSitePlus
C160 S-Nitrosylation dbSNO 24105792
K163 Acetylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
Y191 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y195 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
K199 Sumoylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K206 Sumoylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K268 Acetylation PhosphoSitePlus   UniProt 19608861
K268 Ubiquitination PhosphoSitePlus
K272 Acetylation PhosphoSitePlus
K272 Methylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P49841 (GSK3B) S9 P12236 (SLC25A6) unknown eFIP 28591721
Phosphorylation Q9WV60 (Gsk3b) S9 P12236 (SLC25A6) increased_association eFIP 28591721


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T24 K24 Biomuta DOID:3571 / liver cancer [ icgc ]
S148 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R155 L155 Biomuta DOID:3571 / liver cancer [ icgc ]
T197 M197 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
K268 R268 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]