iPTMnet Report for P12111 (COL6A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12111 / CO6A3_HUMAN
Protein Name Collagen alpha-3(VI) chain precursor
Gene Name Name: COL6A3
Organism Homo sapiens (Human)

PRO ID PR:P12111
DAG View
PRO Name collagen alpha-3(VI) chain (human)
Definition A collagen alpha-3(VI) chain that is encoded in the genome of human.
Short Label hCOL6A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12111 (COL6A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T115 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
T433 Phosphorylation PhosphoSitePlus   UniProt 21406692
T510 Phosphorylation PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
Y543 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
S934 Phosphorylation PhosphoSitePlus
S953 Phosphorylation PhosphoSitePlus
Y1072 Phosphorylation PhosphoSitePlus
N1150 N-Glycosylation GlyGen 29391424
K1156 Acetylation PhosphoSitePlus
S1225 Phosphorylation PhosphoSitePlus   UniProt 24275569
K1231 Acetylation PhosphoSitePlus
K1305 Ubiquitination PhosphoSitePlus
Y1318 Phosphorylation PhosphoSitePlus
S1320 Phosphorylation PhosphoSitePlus
S1348 Phosphorylation PhosphoSitePlus
T1409 Phosphorylation PhosphoSitePlus
T1410 Phosphorylation PhosphoSitePlus
K1418 Acetylation PhosphoSitePlus
T1423 O-Glycosylation GlyGen 30459171
S1471 Phosphorylation PhosphoSitePlus
Y1493 Phosphorylation PhosphoSitePlus
S1512 Phosphorylation PhosphoSitePlus
S1557 Phosphorylation IEDB 35494241
T1619 O-Glycosylation GlyGen 30459171
T1627 O-Glycosylation GlyGen 30459171
S1654 Phosphorylation PhosphoSitePlus
S1737 Phosphorylation PhosphoSitePlus
K1772 Acetylation PhosphoSitePlus
S1783 Phosphorylation PhosphoSitePlus
T1929 Phosphorylation PhosphoSitePlus
S1944 O-Glycosylation GlyGen 28657654, 30620550
S2048 Phosphorylation PhosphoSitePlus
N2079 N-Glycosylation GlyGen   UniProt 29741879, 29391424, 19159218
T2173 Phosphorylation PhosphoSitePlus
N2324 N-Glycosylation GlyGen 29391424
K2464 Acetylation PhosphoSitePlus
S2467 Phosphorylation PhosphoSitePlus
S2492 Phosphorylation PhosphoSitePlus
T2498 Phosphorylation PhosphoSitePlus
K2532 Acetylation PhosphoSitePlus
N2558 N-Glycosylation GlyGen 29741879
T2560 O-Glycosylation GlyGen 28657654, 30620550
Y2641 Phosphorylation PhosphoSitePlus
S2652 Phosphorylation PhosphoSitePlus
N2677 N-Glycosylation GlyGen   UniProt 16335952, 29741879, 29391424, ...19159218
Y2767 Phosphorylation PhosphoSitePlus
S2821 Phosphorylation PhosphoSitePlus
Y2827 Phosphorylation PhosphoSitePlus
S2829 Phosphorylation PhosphoSitePlus
K2943 Acetylation PhosphoSitePlus
T2980 Phosphorylation PhosphoSitePlus
N3037 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
C3060 Methylation IEDB 31844290
S3079 Phosphorylation PhosphoSitePlus
S3100 O-Glycosylation GlyGen 30459171
T3101 O-Glycosylation GlyGen 30459171
Y3142 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y3142 Phosphorylation HPRD 19664994
Site PTM Type PTM Enzyme Score Source PMID
Y2936 Phosphorylation HPRD 19664994
Site PTM Type PTM Enzyme Score Source PMID
K228 Acetylation PhosphoSitePlus
Y2535 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T115 N115 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T115 A115 Biomuta DOID:4159 / skin cancer [ cosmic ]
S561 Y561 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S934 N934 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K1156 N1156 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1409 M1409 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T1410 I1410 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1493 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S1512 P1512 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1557 F1557 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1627 A1627 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1783 L1783 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1783 A1783 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1783 T1783 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T2173 I2173 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2492 L2492 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
Y2535 C2535 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y2535 N2535 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y2535 H2535 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S2829 F2829 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y2936 C2936 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y2936 N2936 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y2936 H2936 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
N3037 K3037 Biomuta DOID:1319 / brain cancer [ cosmic ]
S3079 Y3079 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y3142 C3142 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y3142 N3142 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y3142 H3142 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]