iPTMnet Report for P12036 (NEFH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12036 / NFH_HUMAN
Protein Name Neurofilament heavy polypeptide
Gene Name Name: NEFH
Synonyms:KIAA0845,NFH;
Organism Homo sapiens (Human)

PRO ID PR:P12036
DAG View
PRO Name neurofilament heavy polypeptide (human)
Definition A neurofilament heavy polypeptide that is encoded in the genome of human.
Short Label hNEFH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12036 (NEFH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K31 Ubiquitination PhosphoSitePlus
S54 O-Glycosylation GlyGen 30379171, 28657654, 30397120
S54 Phosphorylation PhosphoSitePlus
S56 O-Glycosylation GlyGen 30379171, 28657654, 30397120
S59 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
R164 Methylation PhosphoSitePlus
T268 O-Glycosylation GlyGen 30379171, 28657654, 30397120
T329 O-Glycosylation GlyGen 30379171
T330 O-Glycosylation GlyGen 30379171
K336 Ubiquitination PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y385 Phosphorylation PhosphoSitePlus
K404 Acetylation PhosphoSitePlus
R412 Methylation PhosphoSitePlus
S421 O-Glycosylation GlyGen 30379171, 28657654, 30397120
S431 Phosphorylation PhosphoSitePlus
T501 Phosphorylation HPRD   PhosphoSitePlus 18510355
S503 Phosphorylation HPRD   PhosphoSitePlus   Signor 18510355, 12130654, 19530163
S503 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 12130654, 19530163
S511 Phosphorylation HPRD   PhosphoSitePlus 18510355
S518 Phosphorylation HPRD   PhosphoSitePlus 18510355, 9592082
S518 Phosphorylation P28482 (MAPK1) HPRD 18510355, 9592082
S526 Phosphorylation HPRD   PhosphoSitePlus 9592082
S526 Phosphorylation P28482 (MAPK1) HPRD 9592082
K531 Ubiquitination PhosphoSitePlus
S532 O-Glycosylation GlyGen 30379171, 28657654, 30397120
S532 Phosphorylation HPRD   PhosphoSitePlus 9592082
S532 Phosphorylation P28482 (MAPK1) HPRD 9592082
S540 Phosphorylation PhosphoSitePlus   UniProt 24275569
S546 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus   UniProt 24275569
S580 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
S614 Phosphorylation HPRD   PhosphoSitePlus 18510355
S620 Phosphorylation HPRD   PhosphoSitePlus 18510355
S628 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18510355, 24275569
S634 Phosphorylation HPRD   PhosphoSitePlus 18510355
S640 Phosphorylation HPRD   PhosphoSitePlus 18510355
T642 O-Glycosylation GlyGen 30379171, 28657654, 30397120
S648 O-Glycosylation GlyGen 30379171, 28657654, 30397120
S648 Phosphorylation HPRD   PhosphoSitePlus 18510355
S654 Phosphorylation HPRD   PhosphoSitePlus 18510355
K657 Phosphorylation PhosphoSitePlus
K659 Acetylation PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
K663 Acetylation PhosphoSitePlus
S668 Phosphorylation HPRD   PhosphoSitePlus 18510355
S674 Phosphorylation PhosphoSitePlus   UniProt 24275569
S682 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus   UniProt 24275569
S696 Phosphorylation PhosphoSitePlus
S702 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
S724 Phosphorylation HPRD   PhosphoSitePlus 18510355
S730 Phosphorylation PhosphoSitePlus
T738 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
S752 Phosphorylation HPRD   PhosphoSitePlus 18510355
S758 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
S793 Phosphorylation phospho.ELM   PhosphoSitePlus 15822905
S801 O-Glycosylation GlyGen 30379171
S801 Phosphorylation phospho.ELM   PhosphoSitePlus 15822905
S807 O-Glycosylation GlyGen 30379171
S807 Phosphorylation PhosphoSitePlus
S828 Phosphorylation PhosphoSitePlus
K895 Ubiquitination PhosphoSitePlus
K907 Acetylation PhosphoSitePlus
K908 Acetylation PhosphoSitePlus
T911 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
S993 Phosphorylation PhosphoSitePlus