iPTMnet Report for P12023 (App)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12023 / A4_MOUSE
Protein Name Amyloid-beta precursor protein precursor
Gene Name Name: App
Synonyms:A4;
Organism Mus musculus (Mouse)

PRO ID PR:P12023
DAG View
PRO Name amyloid-beta precursor protein (mouse)
Definition An amyloid-beta precursor protein that is encoded in the genome of mouse.
Short Label mAPP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12023 (App) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T107 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus   UniProt 21183079
T651 O-Glycosylation GlyGen 22645316
T652 O-Glycosylation GlyGen 22645316
S679 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
K726 Ubiquitination PhosphoSitePlus
T743 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 14722157, 28720718
K751 Ubiquitination PhosphoSitePlus
Y757 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11279131, 11877420, 21849536
Y757 Phosphorylation Q3UFB7 (Ntrk1) PhosphoSitePlus 21849536
Y762 Phosphorylation PhosphoSitePlus
K763 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T292 O-Glycosylation PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
Y653 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
T668 Phosphorylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
Y682 Phosphorylation PhosphoSitePlus 15054097
Y682 Phosphorylation P05480 (Src) PhosphoSitePlus 15054097
Y687 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus