iPTMnet Report for P11766 (ADH5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11766 / ADHX_HUMAN
Protein Name Alcohol dehydrogenase class-3
Gene Name Name: ADH5
Synonyms:ADHX,FDH;
Organism Homo sapiens (Human)

PRO ID PR:P11766
DAG View
PRO Name alcohol dehydrogenase class-3 (human)
Definition An alcohol dehydrogenase class-3 that is encoded in the genome of human.
Short Label hADH5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11766 (ADH5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K7 Ubiquitination PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K101 Acetylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
T127 Phosphorylation HPRD   PhosphoSitePlus 20068231
S128 Phosphorylation HPRD   PhosphoSitePlus 20068231
T131 Phosphorylation HPRD 20068231
K226 Acetylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus   UniProt 24275569
C268 Methylation IEDB 31844290
T303 Phosphorylation HPRD   PhosphoSitePlus 20058876
K315 Acetylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus   UniProt 23186163
K330 Ubiquitination PhosphoSitePlus
K338 Acetylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus   UniProt 23186163
K357 Ubiquitination PhosphoSitePlus
K366 Acetylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S21 F21 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T303 I303 Biomuta DOID:4159 / skin cancer [ cosmic ]
K357 Q357 Biomuta DOID:10534 / stomach cancer [ cosmic ]