iPTMnet Report for P11678 (EPX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11678 / PERE_HUMAN
Protein Name Eosinophil peroxidase precursor
Gene Name Name: EPX
Synonyms:EPER,EPO,EPP;
Organism Homo sapiens (Human)

PRO ID PR:P11678
DAG View
PRO Name eosinophil peroxidase (human)
Definition An eosinophil peroxidase that is encoded in the genome of human.
Short Label hEPX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11678 (EPX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S66 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
N327 N-Glycosylation GlyGen 10864452
N363 N-Glycosylation GlyGen 29741879, 10864452
C370 S-Nitrosylation dbSNO 25040305
Y431 Phosphorylation PhosphoSitePlus
Y451 Phosphorylation PhosphoSitePlus
K594 Methylation PhosphoSitePlus
C635 S-Nitrosylation dbSNO 25040305
S670 Phosphorylation PhosphoSitePlus
S672 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S66 L66 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y75 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S322 L322 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y451 * Biomuta DOID:1319 / brain cancer [ cosmic ]