iPTMnet Report for P11440 (Cdk1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11440 / CDK1_MOUSE
Protein Name Cyclin-dependent kinase 1
Gene Name Name: Cdk1
Synonyms:Cdc2;
Organism Mus musculus (Mouse)

PRO ID PR:P11440
DAG View
PRO Name cyclin-dependent kinase 1 (mouse)
Definition A cyclin-dependent kinase 1 that is encoded in the genome of mouse.
Short Label mCDK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11440 (Cdk1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 23806337
K6 Acetylation UniProt 23806337
K9 Acetylation UniProt 23806337
T14 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19144319, 22067460, 18349838, ...30154440, 21183079, 17242355, 19131326, 22331465
Y15 Phosphorylation P47810 (Wee1) , Q66JT0 (Wee2) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19131326, 21454751, 22948297, ...17242355, 24340001, 16924665, 22331465, 27096953, 25246615, 30626720, 9699647, 35067737, 19144319, 27196784, 27117522, 18349838, 16169490, 21209834, 15580572, 21183079, 19917613, 24551245, 23616086, 22067460, 15592455, 30616572, 17342725, 15459478, 30154440, 31437213, 22319576, 20428502, 18176113, 16329156, 11500387, 21535921, 19933706
Y19 Phosphorylation PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
T161 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 32850387, 22067460, 18176113, ...17242355, 23649674, 33015052
K201 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PRO 17242355
T161 Phosphorylation PRO 17242355


P11440 (Cdk1) as PTM Enzyme



Substrate Site Score Source PMID
O88643 (Pak1) T212 phospho.ELM   PhosphoSitePlus 12176334, 12176333
P00520 (Abl1) T547 PhosphoSitePlus 2183353
P00520 (Abl1) S569 PhosphoSitePlus 2183353
P05480 (Src) S74 PhosphoSitePlus 12801906
P08775 (Polr2a) S1616 phospho.ELM   PhosphoSitePlus 1899239
P08775 (Polr2a) S1619 phospho.ELM   PhosphoSitePlus 1899239
P10085 (Myod1) S5 PhosphoSitePlus 14749395
P10085 (Myod1) S200 phospho.ELM   PhosphoSitePlus 14749395, 10942602, 10082583
P11881 (Itpr1) S421 phospho.ELM 14635192
P11881 (Itpr1) T799 phospho.ELM 14635192
P20152 (Vim) S56 PhosphoSitePlus 16260496
P25206 (Mcm3) S112 phospho.ELM   PhosphoSitePlus 18524952
P25206 (Mcm3) T719 phospho.ELM   PhosphoSitePlus 18524952
P27699 (Crem) S133 PhosphoSitePlus 8404858, 8114763
P27699 (Crem) S156 PhosphoSitePlus 8404858, 8114763
P27699 (Crem) S284 PhosphoSitePlus 8404858, 8114763
P27699 (Crem) S290 PhosphoSitePlus 8404858, 8114763
P28033 (Cebpb) S64 RLIMS-P+ 15314150
P31001 (Des) S31 RLIMS-P+ 27565725
P31938 (Map2k1) T286 RLIMS-P+ 25971971
P31938 (Map2k1) T292 RLIMS-P+ 25971971
P48678 (Lmna) S392 PhosphoSitePlus 8477740
P49717 (Mcm4) T7 phospho.ELM   PhosphoSitePlus 16519687
P49717 (Mcm4) T19 PhosphoSitePlus 16519687
P49717 (Mcm4) S32 phospho.ELM   PhosphoSitePlus 16519687
P49717 (Mcm4) S87 phospho.ELM   PhosphoSitePlus 16519687
P49717 (Mcm4) T109 phospho.ELM   PhosphoSitePlus 16519687
P53566 (Cebpa) S21 PhosphoSitePlus 20516642
P53566 (Cebpa) S193 PhosphoSitePlus 20516642
P62137 (Ppp1ca) T320 PhosphoSitePlus 9122166
Q03147 (Cdk7) S164 PhosphoSitePlus 7553872
Q61337 (Bad) S128 PhosphoSitePlus 12189144
Q61937 (Npm1) T232 Signor 11278991
Q9ERT9 (Ppp1r1a) S67 PhosphoSitePlus 11278334
Q9QY81 (Nup210) S1880 phospho.ELM 8672508
Q9R1E0 (Foxo1) S246 PhosphoSitePlus 18356527
Q9WU62 (Incenp) T59 phospho.ELM 16378098
Q9WU62 (Incenp) T388 phospho.ELM 16378098


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000026212 (mCDK1/iso:1/Phos:2) pT161 PRO 17242355
PR:000026213 (mCDK1/iso:1/Phos:1) pT14 PRO 17242355