iPTMnet Report for P11310 (ACADM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11310 / ACADM_HUMAN
Protein Name Medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor
Gene Name Name: ACADM
Organism Homo sapiens (Human)

PRO ID PR:P11310
DAG View
PRO Name medium-chain specific acyl-CoA dehydrogenase, mitochondrial (human)
Definition A medium-chain specific acyl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human.
Short Label hACADM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11310 (ACADM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K69 Ubiquitination PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K212 Acetylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K279 Acetylation PhosphoSitePlus   UniProt 19608861
K279 Ubiquitination PhosphoSitePlus
T280 O-Glycosylation GlyGen 34229054, 32119511, 28510447, ...33465208, 35008409
T300 Phosphorylation PhosphoSitePlus
K301 Acetylation PhosphoSitePlus   UniProt 19608861
K301 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
R349 Methylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
Y353 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
Y400 Phosphorylation PhosphoSitePlus
K420 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K179 I179 Biomuta DOID:363 / uterine cancer [ icgc ]
Y183 C183 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K217 N217 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K256 E256 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S320 L320 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R349 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y353 D353 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K395 R395 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K420 E420 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K420 T420 Biomuta DOID:9256 / colorectal cancer [ cosmic ]