Protein Information

Cytoscape View


UniProt AC / UniProt ID P11279 / LAMP1_HUMAN
Protein Name Lysosome-associated membrane glycoprotein 1 precursor
Gene Name Name: LAMP1
Organism Homo sapiens (Human)

PRO ID PR:P11279
DAG View
PRO Name lysosome-associated membrane glycoprotein 1 (human)
Definition A lysosome-associated membrane glycoprotein 1 that is encoded in the genome of human.
Short Label hLAMP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11279 (LAMP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation PhosphoSitePlus
N37 N-Glycosylation GlyGen   UniProt 8323299, 29391424
N45 N-Glycosylation GlyGen   UniProt 8323299
N62 N-Glycosylation GlyGen   UniProt 19159218, 24190977, 23090970, ...29391424, 29741879, 12754519, 29671580
S69 Phosphorylation PhosphoSitePlus
T72 Phosphorylation PhosphoSitePlus
N76 N-Glycosylation GlyGen   UniProt 23090970, 2243102, 19159218, ...24190977
S78 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
N84 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 29391424, ...19159218, 24190977
T85 O-Glycosylation GlyGen 23301498, 32119511, 26374642, ...28657654, 29351928
T85 Phosphorylation PhosphoSitePlus
N103 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 32125861, ...24190977, 23090970, 29391424, 23345538, 29741879, 12754519
N107 N-Glycosylation GlyGen   UniProt 23090970, 8323299, 24190977
N121 N-Glycosylation GlyGen   UniProt 23090970, 19159218, 24190977
N130 N-Glycosylation GlyGen   UniProt 23090970, 19159218, 24190977
K137 Ubiquitination PhosphoSitePlus
N164 N-Glycosylation GlyGen 24190977
N165 N-Glycosylation GlyGen   UniProt 23090970, 8323299, 2243102, ...24190977
N181 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...2243102, 8323299
S183 O-Glycosylation GlyGen 8323299
S197 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299
T199 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299, 30459171
T200 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299
S207 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299, 30459171
S209 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299
S211 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299
N223 N-Glycosylation GlyGen   UniProt 8323299
N228 N-Glycosylation GlyGen   UniProt 8323299
T230 Phosphorylation PhosphoSitePlus
N241 N-Glycosylation GlyGen   UniProt 8323299, 23345538, 29741879
N249 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...29391424, 23345538, 29741879
N261 N-Glycosylation GlyGen   UniProt 23090970, 8323299, 24190977, ...2243102, 29741879
N293 N-Glycosylation GlyGen   UniProt 29741879, 19159218
K319 Ubiquitination PhosphoSitePlus
N322 N-Glycosylation GlyGen   UniProt 29741879, 23345538, 8323299, ...29391424, 24190977
T331 O-Glycosylation PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus
K337 Methylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S381 O-Glycosylation GlyGen 23301498, 32119511, 26374642, ...28657654, 29351928
Y414 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S351 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N62 T62 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S69 P69 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S79 Y79 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
S79 C79 Biomuta DOID:263 / kidney cancer [ cosmic ]
N121 K121 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
N181 S181 Biomuta DOID:1324 / lung cancer [ tcga ]
S351 L351 Biomuta DOID:11934 / head and neck cancer [ tcga ]