iPTMnet Report P11279 LAMP1

Protein Information

UniProt AC / UniProt ID	P11279 / LAMP1_HUMAN
Protein Name	Lysosome-associated membrane glycoprotein 1 precursor
Gene Name	Name: LAMP1
Organism	Homo sapiens (Human)

PRO ID	PR:P11279 DAG View
PRO Name	lysosome-associated membrane glycoprotein 1 (human)
Definition	A lysosome-associated membrane glycoprotein 1 that is encoded in the genome of human.
Short Label	hLAMP1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P11279 (LAMP1) as Substrate

Expanded View

Site	PTM Type	Score	Source	PMID
S27	Phosphorylation	score1	PhosphoSitePlus
N37	N-Glycosylation	score4	GlyGen UniProt	8323299, 29391424
N45	N-Glycosylation	score3	GlyGen UniProt	8323299
N62	N-Glycosylation	score2	GlyGen UniProt	19159218, 24190977, 23090970, ...29391424, 29741879, 12754519, 29671580
T64	O-Glycosylation	score1	GlyGen	23301498, 33214551, 26374642, ...34725712, 28657654, 29351928, 34019948, 32119511, 35289036, 33465208, 36240223
S69	O-Glycosylation	score1	GlyGen	23301498, 33214551, 26374642, ...34725712, 28657654, 29351928, 34019948, 32119511, 35289036, 33465208, 36240223
S69	Phosphorylation	score1	PhosphoSitePlus
T72	O-Glycosylation	score1	GlyGen	23301498, 33214551, 26374642, ...34725712, 28657654, 29351928, 34019948, 32119511, 35289036, 33465208, 36240223
T72	Phosphorylation	score1	PhosphoSitePlus
N76	N-Glycosylation	score4	GlyGen UniProt	23090970, 2243102, 19159218, ...24190977
S78	Phosphorylation	score1	PhosphoSitePlus
S79	Phosphorylation	score1	PhosphoSitePlus
N84	N-Glycosylation	score2	GlyGen UniProt	34089345, 19159218, 24190977, ...23090970, 29391424, 29741879
T85	O-Glycosylation	score1	GlyGen	23301498, 33214551, 26374642, ...34725712, 28657654, 29351928, 34019948, 32119511, 35289036, 33465208, 36240223
T85	Phosphorylation	score1	PhosphoSitePlus
N103	N-Glycosylation	score2	GlyGen UniProt	16335952, 34089345, 32125861, ...19159218, 24190977, 23090970, 29391424, 23345538, 29741879, 12754519
T105	O-Glycosylation	score1	GlyGen	23301498, 33214551, 26374642, ...34725712, 28657654, 29351928, 34019948, 32119511, 35289036, 33465208, 36240223
N107	N-Glycosylation	score4	GlyGen UniProt	23090970, 8323299, 24190977
N121	N-Glycosylation	score2	GlyGen UniProt	23090970, 19159218, 24190977
N130	N-Glycosylation	score2	GlyGen UniProt	23090970, 19159218, 24190977
K137	Ubiquitination	score1	PhosphoSitePlus
N164	N-Glycosylation	score1	GlyGen	24190977
N165	N-Glycosylation	score4	GlyGen UniProt	23090970, 8323299, 2243102, ...24190977
N181	N-Glycosylation	score4	GlyGen UniProt	23090970, 29741879, 24190977, ...2243102, 8323299
S183	O-Glycosylation	score2	GlyGen	8323299
S197	O-Glycosylation	score4	GlyGen PhosphoSitePlus UniProt	23584533, 25813380, 8323299
T199	O-Glycosylation	score4	GlyGen PhosphoSitePlus UniProt	23584533, 30459171, 25813380, ...8323299
T200	O-Glycosylation	score4	GlyGen PhosphoSitePlus UniProt	8323299, 25813380, 23584533
S207	O-Glycosylation	score4	GlyGen PhosphoSitePlus UniProt	23301498, 33214551, 26374642, ...34725712, 25813380, 28657654, 29351928, 23584533, 34019948, 33465208, 32119511, 8323299, 35289036, 30459171, 36240223
S209	O-Glycosylation	score4	GlyGen PhosphoSitePlus UniProt	23301498, 33214551, 26374642, ...34725712, 25813380, 28657654, 29351928, 23584533, 34019948, 32119511, 8323299, 35289036, 33465208, 36240223
S211	O-Glycosylation	score4	GlyGen PhosphoSitePlus UniProt	23301498, 33214551, 26374642, ...34725712, 25813380, 28657654, 29351928, 23584533, 34019948, 32119511, 8323299, 35289036, 33465208, 36240223
S216	O-Glycosylation	score1	GlyGen	25813380
S218	O-Glycosylation	score1	GlyGen	25813380
N223	N-Glycosylation	score3	GlyGen UniProt	8323299
N228	N-Glycosylation	score3	GlyGen UniProt	8323299
T230	Phosphorylation	score1	PhosphoSitePlus
N241	N-Glycosylation	score4	GlyGen UniProt	29741879, 23345538, 8323299
N249	N-Glycosylation	score2	GlyGen UniProt	16335952, 19159218, 24190977, ...29391424, 23345538, 29741879
N261	N-Glycosylation	score4	GlyGen UniProt	34089345, 2243102, 24190977, ...23090970, 29741879, 8323299
N293	N-Glycosylation	score2	GlyGen UniProt	29741879, 19159218
K319	Ubiquitination	score1	PhosphoSitePlus
N322	N-Glycosylation	score4	GlyGen UniProt	29741879, 23345538, 8323299, ...29391424, 24190977
T331	O-Glycosylation	score2	GlyGen PhosphoSitePlus	25813380
Y336	Phosphorylation	score1	PhosphoSitePlus
K337	Methylation	score1	PhosphoSitePlus
K337	Ubiquitination	score1	PhosphoSitePlus
S351	Phosphorylation	score1	PhosphoSitePlus
S381	O-Glycosylation	score1	GlyGen	23301498, 33214551, 26374642, ...34725712, 28657654, 29351928, 34019948, 32119511, 35289036, 33465208, 36240223
Y414	Phosphorylation	score1	PhosphoSitePlus
T416	Phosphorylation	score1	PhosphoSitePlus

Site	PTM Type	Score	Source	PMID
N62	N-Glycosylation	score1	PRO	29671580
N84	N-Glycosylation	score1	PRO	29741879
N103	N-Glycosylation	score1	PRO	29741879, 23345538
N241	N-Glycosylation	score1	PRO	23345538
N249	N-Glycosylation	score1	PRO	29741879, 23345538
N261	N-Glycosylation	score1	PRO	29741879
N322	N-Glycosylation	score1	PRO	23345538
S351	Phosphorylation	score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	Disease [Sample source]
N45	S45	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S69	P69	Biomuta	DOID:263 / kidney cancer [ cosmic, icgc ]
S79	Y79	Biomuta	DOID:1319 / brain cancer [ cosmic, icgc ]
S79	C79	Biomuta	DOID:263 / kidney cancer [ cosmic ]
N103	H103	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
T105	M105	Biomuta	DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
N121	K121	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
N181	S181	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
T331	P331	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S351	L351	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for P11279 (LAMP1)

Protein Information

Interactive Sequence View

P11279 (LAMP1) as Substrate

PTM sites affected in variants