iPTMnet Report for P11233 (RALA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11233 / RALA_HUMAN
Protein Name Ras-related protein Ral-A precursor
Gene Name Name: RALA
Synonyms:RAL;
Organism Homo sapiens (Human)

PRO ID PR:P11233
DAG View
PRO Name Ras-related protein Ral-A (human)
Definition A Ras-related protein Ral-A that is encoded in the genome of human.
Short Label hRALA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11233 (RALA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
S11 Phosphorylation HPRD   PhosphoSitePlus 17540176
S22 Phosphorylation PhosphoSitePlus
Y43 Phosphorylation PhosphoSitePlus
T46 O-Glycosylation UniProt 8858106
Y51 Phosphorylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
S183 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 17540176, 30995277
S194 Phosphorylation O14965 (AURKA) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 30070631, 30500825, 19901077, ...21822277, 15637052, 24222664, 30995277


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P11233 (RALA) S194 Q15311 (RALBP1) increased_association eFIP 22545232


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K7 E7 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S11 F11 Biomuta DOID:4159 / skin cancer [ cosmic ]
S11 Y11 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
Y75 C75 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y82 C82 Biomuta DOID:4159 / skin cancer [ cosmic ]
K128 I128 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K134 E134 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S183 G183 Biomuta DOID:4362 / cervical cancer [ icgc ]