Protein Information

Cytoscape View


UniProt AC / UniProt ID P11229 / ACM1_HUMAN
Protein Name Muscarinic acetylcholine receptor M1
Gene Name Name: CHRM1
Organism Homo sapiens (Human)

PRO ID PR:P11229
DAG View
PRO Name muscarinic acetylcholine receptor M1 (human)
Definition A muscarinic acetylcholine receptor M1 that is encoded in the genome of human.
Short Label hCHRM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11229 (CHRM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
K332 Acetylation PhosphoSitePlus
K339 Acetylation PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S273 N273 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S273 R273 Biomuta DOID:363 / uterine cancer [ tcga ]