iPTMnet Report for P11217 (PYGM)
Protein Information
| UniProt AC / UniProt ID | P11217 / PYGM_HUMAN |
| Protein Name | Glycogen phosphorylase, muscle form |
| Gene Name | Name: PYGM |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P11217 |
| PRO Name | glycogen phosphorylase, muscle form (human) |
| Definition | A glycogen phosphorylase, muscle form that is encoded in the genome of human. |
| Short Label | hPYGM |
| Category | organism-gene |
P11217 (PYGM) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R11 | Methylation | score1 | PhosphoSitePlus | |||
| S15 | Phosphorylation | Q16816 (PHKG1) , P15735 (PHKG2) | score4 | phospho.ELM PhosphoSitePlus Signor UniProt | 1150650, 16083285, 1140412, ... | |
| T26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y91 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K316 | Acetylation | score1 | PhosphoSitePlus | |||
| T372 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S430 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S450 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y473 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S514 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S524 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K537 | Acetylation | score1 | PhosphoSitePlus | |||
| K575 | Acetylation | score1 | PhosphoSitePlus | |||
| T603 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K609 | Acetylation | score1 | PhosphoSitePlus | |||
| Y614 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K618 | Acetylation | score1 | PhosphoSitePlus | |||
| T625 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y732 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y733 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S789 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y792 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R11 | K11 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S15 | N15 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y76 | H76 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S87 | F87 | Biomuta | DOID:3565 / meningioma [ cosmic ] | |
| K483 | N483 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ] | |
| Y614 | H614 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K618 | N618 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y732 | H732 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y733 | C733 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View