Protein Information

Cytoscape View


UniProt AC / UniProt ID P11137 / MTAP2_HUMAN
Protein Name Microtubule-associated protein 2
Gene Name Name: MAP2
Organism Homo sapiens (Human)

PRO ID PR:P11137
DAG View
PRO Name microtubule-associated protein 2 (human)
Definition A microtubule-associated protein 2 that is encoded in the genome of human.
Short Label hMAP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11137 (MAP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S63 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T66 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation P07948 (LYN) , P06241 (FYN) phospho.ELM   PhosphoSitePlus   RLIMS-P 15536091
S136 Phosphorylation PhosphoSitePlus   RLIMS-P 7525290
T168 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
S385 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
T427 Phosphorylation PhosphoSitePlus
T516 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
Y593 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
S821 Phosphorylation PhosphoSitePlus
S823 Phosphorylation PhosphoSitePlus
S833 Phosphorylation phospho.ELM   PhosphoSitePlus 15822905
S843 Phosphorylation PhosphoSitePlus
T860 Phosphorylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus
S881 Phosphorylation PhosphoSitePlus
S913 Phosphorylation PhosphoSitePlus
Y996 Phosphorylation PhosphoSitePlus
S1005 Phosphorylation PhosphoSitePlus
S1021 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
S1106 Phosphorylation PhosphoSitePlus
T1108 Phosphorylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
T1154 Phosphorylation PhosphoSitePlus
S1155 Phosphorylation PhosphoSitePlus
S1158 Phosphorylation PhosphoSitePlus
S1234 Phosphorylation PhosphoSitePlus
S1324 Phosphorylation PhosphoSitePlus
S1347 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1353 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1366 Phosphorylation PhosphoSitePlus
T1368 Phosphorylation PhosphoSitePlus
Y1369 Phosphorylation PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus
S1421 Phosphorylation PhosphoSitePlus
K1427 Acetylation PhosphoSitePlus
S1439 Phosphorylation PhosphoSitePlus
T1440 Phosphorylation PhosphoSitePlus
K1447 Ubiquitination PhosphoSitePlus
K1448 Ubiquitination PhosphoSitePlus
S1480 Phosphorylation PhosphoSitePlus
Y1493 Phosphorylation PhosphoSitePlus
T1494 Phosphorylation PhosphoSitePlus
T1497 Phosphorylation PhosphoSitePlus
S1500 Phosphorylation PhosphoSitePlus
K1505 Acetylation PhosphoSitePlus
T1506 Phosphorylation PhosphoSitePlus
K1524 Acetylation PhosphoSitePlus
S1534 Phosphorylation PhosphoSitePlus
S1539 Phosphorylation PhosphoSitePlus
S1540 Phosphorylation PhosphoSitePlus
S1545 Phosphorylation PhosphoSitePlus
S1546 Phosphorylation PhosphoSitePlus
R1552 Methylation PhosphoSitePlus
S1555 Phosphorylation PhosphoSitePlus
S1562 Phosphorylation PhosphoSitePlus
S1564 Phosphorylation PhosphoSitePlus
S1588 Phosphorylation PhosphoSitePlus
T1590 Phosphorylation PhosphoSitePlus
S1591 Phosphorylation PhosphoSitePlus
T1592 Phosphorylation PhosphoSitePlus
T1594 Phosphorylation PhosphoSitePlus
T1595 Phosphorylation PhosphoSitePlus
S1598 Phosphorylation PhosphoSitePlus
T1599 Phosphorylation PhosphoSitePlus
T1602 Phosphorylation PhosphoSitePlus
T1605 Phosphorylation PhosphoSitePlus
S1608 Phosphorylation PhosphoSitePlus
Y1609 Phosphorylation PhosphoSitePlus
S1611 Phosphorylation PhosphoSitePlus
T1613 Phosphorylation PhosphoSitePlus
T1616 Phosphorylation PhosphoSitePlus
T1619 Phosphorylation PhosphoSitePlus
S1621 Phosphorylation PhosphoSitePlus
Y1622 Phosphorylation PhosphoSitePlus
T1628 Phosphorylation PhosphoSitePlus
T1631 Phosphorylation PhosphoSitePlus
S1634 Phosphorylation PhosphoSitePlus
S1640 Phosphorylation PhosphoSitePlus
T1649 Phosphorylation PhosphoSitePlus
S1653 Phosphorylation PhosphoSitePlus
T1656 Phosphorylation PhosphoSitePlus
S1675 Phosphorylation PhosphoSitePlus
S1679 Phosphorylation P17612 (PRKACA) , Q9P0L2 (MARK1) neXtProt   PhosphoSitePlus   Signor 11029056, 8631898
T1680 Phosphorylation PhosphoSitePlus
K1688 Methylation PhosphoSitePlus
S1702 Phosphorylation PhosphoSitePlus
S1706 Phosphorylation PhosphoSitePlus
S1710 Phosphorylation Q9P0L2 (MARK1) , P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 11029056, 8631898
K1724 Methylation PhosphoSitePlus
S1727 Phosphorylation PhosphoSitePlus
S1742 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   Signor 11029056
T1780 Phosphorylation PhosphoSitePlus
S1782 Phosphorylation P17612 (PRKACA) phospho.ELM   PhosphoSitePlus   Signor   UniProt 11029056, 24275569, 18220336
S1786 Phosphorylation PhosphoSitePlus
S1787 Phosphorylation PhosphoSitePlus
S1790 Phosphorylation PhosphoSitePlus
S1795 Phosphorylation PhosphoSitePlus
S1798 Phosphorylation PhosphoSitePlus
S1799 Phosphorylation PhosphoSitePlus
S1800 Phosphorylation PhosphoSitePlus
S1802 Phosphorylation PhosphoSitePlus
S1808 Phosphorylation PhosphoSitePlus
T1813 Phosphorylation PhosphoSitePlus
T1819 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S63 Phosphorylation HPRD 17525332
S610 Phosphorylation HPRD 15345747
S654 Phosphorylation HPRD 15345747
S729 Phosphorylation HPRD 15345747
S821 Phosphorylation HPRD 15345747
T1154 Phosphorylation HPRD 19415658
S1155 Phosphorylation HPRD 18510355
S1234 Phosphorylation HPRD 18510355
S1347 Phosphorylation HPRD 18510355, 15345747
S1353 Phosphorylation HPRD 18510355
S1540 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
T1594 Phosphorylation HPRD 15345747
T1602 Phosphorylation HPRD 15345747
T1605 Phosphorylation HPRD 15345747
S1608 Phosphorylation HPRD 15345747
T1619 Phosphorylation HPRD 20058876, 18212344
S1675 Phosphorylation P17612 (PRKACA) HPRD 11029056
S1679 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
S1710 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
T1780 Phosphorylation HPRD 19415658
S1782 Phosphorylation HPRD 20166139, 18707149, 19415658, ...18212344
S1795 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
S1798 Phosphorylation HPRD 17081983
S1799 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
S1800 Phosphorylation HPRD 17081983
S1802 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
Site PTM Type PTM Enzyme Score Source PMID
S63 Phosphorylation HPRD 17525332
Y67 Phosphorylation P06241 (FYN) neXtProt   PhosphoSitePlus 15536091
S184 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
T236 Phosphorylation PhosphoSitePlus
T238 Phosphorylation HPRD 15345747
T246 Phosphorylation HPRD 15345747
T249 Phosphorylation HPRD 15345747
S252 Phosphorylation HPRD 15345747
T263 Phosphorylation HPRD 20058876, 18212344
S319 Phosphorylation P17612 (PRKACA) HPRD 11029056
S323 Phosphorylation Q9P0L2 (MARK1) HPRD   neXtProt 11029056, 8631898
S354 Phosphorylation Q9P0L2 (MARK1) HPRD   neXtProt 11029056, 8631898
T424 Phosphorylation HPRD 19415658
S426 Phosphorylation HPRD   neXtProt 20166139, 11029056, 18707149, ...19415658, 18212344
S439 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
S442 Phosphorylation HPRD 17081983
S443 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
S444 Phosphorylation HPRD 17081983
S446 Phosphorylation Q9P0L2 (MARK1) HPRD 8631898
Site PTM Type PTM Enzyme Score Source PMID
Y50 Phosphorylation P06241 (FYN) PhosphoSitePlus 16145685
Y67 Phosphorylation P06241 (FYN) PhosphoSitePlus 16145685
T286 Phosphorylation PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
K1423 Acetylation PhosphoSitePlus
T1588 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S63 Phosphorylation HPRD 17525332
S188 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
T320 Phosphorylation HPRD 20058876, 18212344
S411 Phosphorylation PhosphoSitePlus
K412 Methylation PhosphoSitePlus
K416 Methylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
T512 Phosphorylation HPRD 19415658
S514 Phosphorylation HPRD 20166139, 18707149, 19415658, ...18212344
S527 Phosphorylation HPRD 17081983
S530 Phosphorylation HPRD 17081983
S531 Phosphorylation HPRD 17081983
S532 Phosphorylation HPRD 17081983
S534 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S136 C136 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S136 Y136 Biomuta DOID:10534 / stomach cancer [ icgc ]
T216 M216 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S233 I233 Biomuta DOID:3571 / liver cancer [ icgc ]
S285 Y285 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:10534 / stomach cancer [ icgc, tcga ]
T290 N290 Biomuta DOID:3070 / malignant glioma [ tcga ]
S315 R315 Biomuta DOID:5041 / esophageal cancer [ icgc ]
T323 N323 Biomuta DOID:363 / uterine cancer [ tcga ]
S629 I629 Biomuta DOID:363 / uterine cancer [ tcga ]
S654 Y654 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S725 P725 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S729 F729 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S785 * Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S823 N823 Biomuta DOID:1909 / melanoma [ cosmic ]
S833 L833 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S833 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T860 M860 Biomuta DOID:5041 / esophageal cancer [ tcga ] DOID:0070003 / blastoma [ cosmic ]
S881 P881 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S913 L913 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1158 L1158 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1234 N1234 Biomuta DOID:1909 / melanoma [ cosmic ]
S1347 F1347 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S1353 Y1353 Biomuta DOID:3571 / liver cancer [ icgc ]
T1368 P1368 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S1420 L1420 Biomuta DOID:1612 / breast cancer [ tcga ]
T1494 S1494 Biomuta DOID:1324 / lung cancer [ tcga ]
S1539 T1539 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S1546 F1546 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R1552 * Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S1564 C1564 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1591 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
T1602 S1602 Biomuta DOID:1324 / lung cancer [ icgc ]
T1605 N1605 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1611 L1611 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S1706 A1706 Biomuta DOID:1324 / lung cancer [ tcga ]
S1786 Y1786 Biomuta DOID:0060119 / pharynx cancer [ cosmic ]
S1786 T1786 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1786 C1786 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1798 Y1798 Biomuta DOID:1909 / melanoma [ tcga ]
S1799 L1799 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:1909 / melanoma [ icgc, tcga ]
S1800 F1800 Biomuta DOID:363 / uterine cancer [ tcga ]
S1802 N1802 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]