Protein Information

Cytoscape View


UniProt AC / UniProt ID P11117 / PPAL_HUMAN
Protein Name Lysosomal acid phosphatase precursor
Gene Name Name: ACP2
Organism Homo sapiens (Human)

PRO ID PR:P11117
DAG View
PRO Name lysosomal acid phosphatase (human)
Definition A lysosomal acid phosphatase that is encoded in the genome of human.
Short Label hACP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11117 (ACP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
N92 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N133 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K153 Ubiquitination PhosphoSitePlus
N167 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N177 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S179 O-Glycosylation GlyGen 30237853
N191 N-Glycosylation GlyGen   UniProt 3056714
N267 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N322 N-Glycosylation GlyGen   UniProt 3056714
N331 N-Glycosylation GlyGen   UniProt 19159218


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S46 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
N92 K92 Biomuta DOID:3571 / liver cancer [ icgc ]
N167 S167 Biomuta DOID:3070 / malignant glioma [ tcga ]