iPTMnet Report for P11055 (MYH3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11055 / MYH3_HUMAN
Protein Name Myosin-3
Gene Name Name: MYH3
Organism Homo sapiens (Human)

PRO ID PR:P11055
DAG View
PRO Name myosin-3 (human)
Definition A myosin-3 that is encoded in the genome of human.
Short Label hMYH3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11055 (MYH3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C38 Methylation IEDB 31844290
K44 Acetylation PhosphoSitePlus
Y78 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
T379 Phosphorylation PhosphoSitePlus
Y411 Phosphorylation PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
K414 Acetylation PhosphoSitePlus
K503 Acetylation PhosphoSitePlus
Y554 Phosphorylation PhosphoSitePlus
Y610 Phosphorylation PhosphoSitePlus
Y716 Phosphorylation PhosphoSitePlus
Y723 Phosphorylation PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
Y817 Phosphorylation PhosphoSitePlus
K832 Acetylation PhosphoSitePlus
K842 Acetylation PhosphoSitePlus
T852 Phosphorylation PhosphoSitePlus
T860 Phosphorylation PhosphoSitePlus
K872 Acetylation PhosphoSitePlus
S949 Phosphorylation PhosphoSitePlus
K952 Acetylation PhosphoSitePlus
K953 Acetylation PhosphoSitePlus
T961 Phosphorylation PhosphoSitePlus
S984 Phosphorylation PhosphoSitePlus
S1066 Phosphorylation PhosphoSitePlus
C1089 Methylation IEDB 31844290
T1129 Phosphorylation PhosphoSitePlus
T1133 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
Y1140 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
S1336 Phosphorylation PhosphoSitePlus
S1367 Phosphorylation PhosphoSitePlus
T1374 Phosphorylation PhosphoSitePlus
Y1376 Phosphorylation PhosphoSitePlus
T1378 Phosphorylation PhosphoSitePlus
T1384 Phosphorylation PhosphoSitePlus
K1391 Acetylation PhosphoSitePlus
K1392 Acetylation PhosphoSitePlus
K1393 Acetylation PhosphoSitePlus
T1418 Phosphorylation PhosphoSitePlus
S1477 Phosphorylation PhosphoSitePlus
S1479 Phosphorylation PhosphoSitePlus
T1480 Phosphorylation PhosphoSitePlus
Y1489 Phosphorylation PhosphoSitePlus
T1733 Phosphorylation HPRD   PhosphoSitePlus 18452278
S1740 Phosphorylation HPRD   PhosphoSitePlus 18452278
T1761 Phosphorylation PhosphoSitePlus
K1771 Acetylation PhosphoSitePlus
K1832 Acetylation PhosphoSitePlus
K1877 Acetylation PhosphoSitePlus
K1880 Acetylation PhosphoSitePlus
S1916 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y78 * Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
Y110 F110 Biomuta [ cosmic ]
T354 M354 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
Y360 * Biomuta DOID:1319 / brain cancer [ cosmic ]
K414 E414 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y716 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K842 N842 Biomuta DOID:4159 / skin cancer [ cosmic ]
T860 I860 Biomuta DOID:4159 / skin cancer [ cosmic ]
K953 E953 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1066 F1066 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1138 R1138 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1367 N1367 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1367 G1367 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1392 R1392 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1479 N1479 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1761 M1761 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1916 F1916 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]