iPTMnet Report for P10911 (MCF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P10911 / MCF2_HUMAN
Protein Name Proto-oncogene DBL
Gene Name Name: MCF2
Synonyms:DBL;
Organism Homo sapiens (Human)

PRO ID PR:P10911
DAG View
PRO Name proto-oncogene DBL (human)
Definition A proto-oncogene DBL that is encoded in the genome of human.
Short Label hMCF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P10911 (MCF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S412 O-Glycosylation GlyGen 36240223
S412 Phosphorylation PhosphoSitePlus
Y510 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
K693 Acetylation PhosphoSitePlus
K708 Acetylation PhosphoSitePlus
T711 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
Y787 Phosphorylation PhosphoSitePlus
S792 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation HPRD 18452278
T41 Phosphorylation HPRD 18452278
S48 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T39 P39 Biomuta DOID:363 / uterine cancer [ icgc ]
T41 I41 Biomuta DOID:3571 / liver cancer [ cosmic ]
S48 T48 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K406 N406 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S412 I412 Biomuta DOID:363 / uterine cancer [ icgc ]
Y510 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S655 Y655 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K693 M693 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y787 C787 Biomuta DOID:9256 / colorectal cancer [ cosmic ]