iPTMnet Report for P10746 (UROS)
Protein Information
| UniProt AC / UniProt ID | P10746 / HEM4_HUMAN |
| Protein Name | Uroporphyrinogen-III synthase |
| Gene Name | Name: UROS |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P10746 |
| PRO Name | uroporphyrinogen-III synthase (human) |
| Definition | A uroporphyrinogen-III synthase that is encoded in the genome of human. |
| Short Label | hUROS |
| Category | organism-gene |
DAG ViewP10746 (UROS) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K7 | Acetylation | score1 | PhosphoSitePlus | |||
| Y19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S245 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K7 | Q7 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| K124 | T124 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
