iPTMnet Report for P10643 (C7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P10643 / CO7_HUMAN
Protein Name Complement component C7 precursor
Gene Name Name: C7
Organism Homo sapiens (Human)

PRO ID PR:P10643
DAG View
PRO Name complement component C7 (human)
Definition A complement component C7 that is encoded in the genome of human.
Short Label hC7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P10643 (C7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
W36 C-Glycosylation GlyGen   UniProt 10551839
N202 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 14760718, ...29741879
S228 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
W503 C-Glycosylation GlyGen   UniProt 10551839
W506 C-Glycosylation GlyGen   UniProt 10551839
W509 C-Glycosylation GlyGen   UniProt 10551839
T696 O-Glycosylation GlyGen   UniProt 22171320
N754 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19139490, ...29671580
S834 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N754 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
W36 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S228 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S229 L229 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S331 L331 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
W503 L503 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
W503 * Biomuta DOID:4159 / skin cancer [ cosmic ]
W506 L506 Biomuta DOID:1612 / breast cancer [ cosmic ]
W509 C509 Biomuta DOID:1324 / lung cancer [ cosmic ]
N754 Y754 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]