iPTMnet Report for P10635 (CYP2D6)
Protein Information
| UniProt AC / UniProt ID | P10635 / CP2D6_HUMAN |
| Protein Name | Cytochrome P450 2D6 |
| Gene Name | Name: CYP2D6 Synonyms:CYP2DL1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P10635 |
| PRO Name | cytochrome P450 2D6 (human) |
| Definition | A cytochrome P450 2D6 that is encoded in the genome of human. |
| Short Label | hCYP2D6 |
| Category | organism-gene |
DAG ViewP10635 (CYP2D6) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y124 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 26574146 | ||
| S217 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y124 | C124 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| S217 | L217 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] |
