Protein Information

Cytoscape View


UniProt AC / UniProt ID P10619 / PPGB_HUMAN
Protein Name Lysosomal protective protein precursor
Gene Name Name: CTSA
Synonyms:PPGB;
Organism Homo sapiens (Human)

PRO ID PR:P10619
DAG View
PRO Name lysosomal protective protein (human)
Definition A lysosomal protective protein that is encoded in the genome of human.
Short Label hCTSA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P10619 (CTSA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K55 Methylation PhosphoSitePlus
N145 N-Glycosylation UniProt 16263699, 19159218
T295 Phosphorylation PhosphoSitePlus
N333 N-Glycosylation UniProt 19159218
K429 Ubiquitination PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N333 K333 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S472 Y472 Biomuta DOID:1324 / lung cancer [ tcga ]