Protein Information

Cytoscape View

UniProt AC / UniProt ID P10619 / PPGB_HUMAN
Protein Name Lysosomal protective protein precursor
Gene Name Name: CTSA
Organism Homo sapiens (Human)

PRO ID PR:P10619
DAG View
PRO Name lysosomal protective protein (human)
Definition A lysosomal protective protein that is encoded in the genome of human.
Short Label hCTSA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P10619 (CTSA) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K55 Methylation PhosphoSitePlus
N145 N-Glycosylation GlyGen   UniProt 16263699, 29741879, 19159218, ...24190977
N153 N-Glycosylation GlyGen 24190977
N244 N-Glycosylation GlyGen 24190977
T295 Phosphorylation PhosphoSitePlus
N333 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
N351 N-Glycosylation GlyGen 23090970, 24190977
K429 Ubiquitination PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N333 K333 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S472 Y472 Biomuta DOID:1324 / lung cancer [ tcga ]