iPTMnet Report for P10600 (TGFB3)
Protein Information
| UniProt AC / UniProt ID | P10600 / TGFB3_HUMAN |
| Protein Name | Transforming growth factor beta-3 proprotein precursor |
| Gene Name | Name: TGFB3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P10600 |
| PRO Name | transforming growth factor beta-3 (human) |
| Definition | A TGF-beta 3 that is encoded in the genome of human. |
| Short Label | hTGFB3 |
| Category | organism-gene |
DAG ViewP10600 (TGFB3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N135 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| K162 | Methylation | score1 | PhosphoSitePlus | |||
| Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Q293 | Methylation | score1 | UniProt | 26797129 | ||
| K299 | Acetylation | score1 | PhosphoSitePlus | |||
| T357 | O-Glycosylation | score1 | GlyGen | 25813380 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y185 | S185 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Q293 | H293 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K299 | E299 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T357 | A357 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
