iPTMnet Report P10144 GZMB

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P10144 / GRAB_HUMAN
Protein Name	Granzyme B precursor
Gene Name	Name: GZMB Synonyms:CGL1,CSPB,CTLA1;
Organism	Homo sapiens (Human)

PRO ID	PR:P10144 DAG View
PRO Name	granzyme B (human)
Definition	A granzyme B that is encoded in the genome of human.
Short Label	hGZMB
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P10144 (GZMB) as Substrate

P10144

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N71	N-Glycosylation		score3	GlyGen UniProt	11325591
	N104	N-Glycosylation		score3	GlyGen UniProt	11325591
	T150	Phosphorylation		score1	PhosphoSitePlus
	S175	O-Glycosylation		score1	GlyGen	29351928

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N104	K104	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]
T150	M150	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]