iPTMnet Report for P10073 (ZSCAN22)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P10073 / ZSC22_HUMAN
Protein Name Zinc finger and SCAN domain-containing protein 22
Gene Name Name: ZSCAN22
Synonyms:HKR2,ZNF50;
Organism Homo sapiens (Human)

PRO ID PR:P10073
DAG View
PRO Name zinc finger and SCAN domain-containing protein 22 (human)
Definition A zinc finger and SCAN domain-containing protein 22 that is encoded in the genome of human.
Short Label hZSCAN22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P10073 (ZSCAN22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus   UniProt 23186163
S32 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
K133 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
K353 Sumoylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
T403 Phosphorylation PhosphoSitePlus
K443 Sumoylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K133 N133 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
K303 R303 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T375 M375 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T459 M459 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]