iPTMnet Report for P0DPH7 (TUBA3C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P0DPH7 / TBA3C_HUMAN
Protein Name Tubulin alpha-3C chain
Gene Name Name: TUBA3C
Synonyms:TUBA2;
Organism Homo sapiens (Human)

PRO ID PR:P0DPH7
DAG View
PRO Name tubulin alpha-3C chain (human)
Definition A tubulin alpha-3 chain (human) that is a translation product of the TUBA3C gene in human.
Short Label hTUBA3C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P0DPH7 (TUBA3C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K40 Acetylation PhosphoSitePlus   UniProt 24906155
K40 Ubiquitination PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K60 Acetylation PhosphoSitePlus
K60 Sumoylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
R79 Methylation PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K96 Sumoylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
R156 Methylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K163 Methylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
C213 Methylation IEDB 31844290
R221 Methylation IEDB 32357974
T223 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
Y272 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K280 Acetylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
C295 Methylation IEDB 31844290
K304 Ubiquitination PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
K326 Acetylation PhosphoSitePlus
K326 Sumoylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
K336 Acetylation PhosphoSitePlus
K336 Sumoylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
T337 Phosphorylation PhosphoSitePlus
K338 Methylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K352 Sumoylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
K370 Acetylation PhosphoSitePlus
K370 Sumoylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
C376 Methylation IEDB 31844290
S379 Phosphorylation PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
K394 Sumoylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
Y399 Phosphorylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K401 Sumoylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
Y408 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation HPRD 17924679, 18452278
Y282 Phosphorylation HPRD 17016520


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y24 F24 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T51 M51 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T51 P51 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S54 G54 Biomuta DOID:1324 / lung cancer [ cosmic ]
R79 H79 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R79 C79 Biomuta DOID:363 / uterine cancer [ cosmic ]
T80 I80 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y83 S83 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y103 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y108 C108 Biomuta DOID:363 / uterine cancer [ icgc ]
R156 L156 Biomuta DOID:1324 / lung cancer [ cosmic ]
R156 Q156 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
R156 W156 Biomuta DOID:1319 / brain cancer [ cosmic ]
S158 * Biomuta DOID:1612 / breast cancer [ cosmic ]
Y161 H161 Biomuta DOID:4159 / skin cancer [ cosmic ]
K163 N163 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K164 T164 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
K164 R164 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K166 N166 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S187 F187 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y210 H210 Biomuta DOID:1319 / brain cancer [ cosmic ]
R221 S221 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
R221 H221 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T223 M223 Biomuta DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S237 F237 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T253 R253 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T253 M253 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T257 I257 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y262 C262 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y262 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S277 L277 Biomuta DOID:4159 / skin cancer [ cosmic ]
K280 M280 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y282 N282 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y282 C282 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S287 F287 Biomuta DOID:3571 / liver cancer [ cosmic ]
C295 Y295 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K304 M304 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K304 T304 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K311 T311 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K311 N311 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K326 I326 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T337 N337 Biomuta DOID:3571 / liver cancer [ cosmic ]
T340 N340 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T361 M361 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K370 T370 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
C376 F376 Biomuta [ cosmic ]
S379 R379 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y399 H399 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y399 C399 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y408 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y408 C408 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S419 F419 Biomuta DOID:1324 / lung cancer [ cosmic ]