iPTMnet Report for P0DPD6 (ECE2)
Protein Information
| UniProt AC / UniProt ID | P0DPD6 / ECE2_HUMAN |
| Protein Name | Endothelin-converting enzyme 2 |
| Gene Name | Name: ECE2 Synonyms:KIAA0604;ORFNames:UNQ403/PRO740; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P0DPD6 |
| PRO Name | endothelin-converting enzyme 2 (human) |
| Definition | An endothelin-converting enzyme 2 that is encoded in the genome of human. |
| Short Label | hECE2 |
| Category | organism-gene |
DAG ViewP0DPD6 (ECE2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C74 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S48 | F48 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| C74 | S74 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
