iPTMnet Report for P0DP91 (ERCC6)
Protein Information
| UniProt AC / UniProt ID | P0DP91 / ERPG3_HUMAN |
| Protein Name | Chimeric ERCC6-PGBD3 protein |
| Gene Name | Name: ERCC6 |
| Organism | Homo sapiens (Human) |
P0DP91 (ERCC6) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K32 | Sumoylation | score1 | PhosphoSitePlus | |||
| K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163, 16964243, ... | ||
| S212 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T303 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S429 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 21406692 | ||
| S430 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 21406692 | ||
| S554 | Phosphorylation | score1 | UniProt | 23186163 | ||
| K976 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T303 | A303 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K976 | T976 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
