iPTMnet Report for P0DP24 (CALM2)
Protein Information
UniProt AC / UniProt ID | P0DP24 / CALM2_HUMAN |
Protein Name | Calmodulin-2 |
Gene Name | Name: CALM2 Synonyms:CAM2,CAMB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P0DP24 |
PRO Name | calmodulin-2 (human) |
Definition | A calmodulin (human) that is a translation product of the CALM2 gene. |
Short Label | hCALM2 |
Category | organism-gene |
P0DP24 (CALM2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score3 | UniProt | 19413330, 22814378, 22223895, ... | ||
K22 | Acetylation | score1 | UniProt | 19608861 | ||
S82 | Phosphorylation | score1 | UniProt | 23186163 | ||
K95 | Acetylation | score1 | UniProt | 19608861 | ||
Y100 | Phosphorylation | P00533 (EGFR) , P06213 (INSR) | score4 | Signor UniProt | 18669648, 3415247, 19690332 | |
S102 | Phosphorylation | score1 | UniProt | 21406692, 23186163, 24275569 | ||
T111 | Phosphorylation | score1 | UniProt | 24275569 | ||
K116 | Methylation | score1 | UniProt | 24129315 | ||
Y139 | Phosphorylation | score1 | UniProt | 19690332 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K95 | E95 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
Y139 | F139 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y139 | C139 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] |