Protein Information

Cytoscape View


UniProt AC / UniProt ID P0CG47 / UBB_HUMAN
Protein Name Polyubiquitin-B precursor
Gene Name Name: UBB
Organism Homo sapiens (Human)

PRO ID PR:P0CG47
DAG View
PRO Name polyubiquitin-B (human)
Definition A polyubiquitin-B that is encoded in the genome of human.
Short Label hUBB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P0CG47 (UBB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation PhosphoSitePlus
K6 Methylation PhosphoSitePlus
K6 Sumoylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus   UniProt 16443603
T7 Phosphorylation PhosphoSitePlus
K11 Acetylation PhosphoSitePlus
K11 Sumoylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus   UniProt 16443603, 16543144
T12 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
K27 Sumoylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus   UniProt 15466860
K29 Sumoylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus   UniProt 16543144
K33 Sumoylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K48 Acetylation PhosphoSitePlus
K48 Sumoylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus   UniProt 16443603, 16543144
S57 Phosphorylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
K63 Methylation PhosphoSitePlus
K63 Sumoylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus   UniProt 16543144, 18719106
S65 Phosphorylation PhosphoSitePlus   UniProt 24784582, 24660806, 24751536, ...25527291
T66 Phosphorylation PhosphoSitePlus
R72 Methylation PhosphoSitePlus
K82 Acetylation PhosphoSitePlus
K82 Methylation PhosphoSitePlus
K82 Sumoylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
K87 Sumoylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
K103 Sumoylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K105 Sumoylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K109 Sumoylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K124 Acetylation PhosphoSitePlus
K124 Sumoylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
K139 Methylation PhosphoSitePlus
K139 Sumoylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
R148 Methylation PhosphoSitePlus
K158 Acetylation PhosphoSitePlus
K158 Methylation PhosphoSitePlus
K158 Sumoylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
T159 Phosphorylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K163 Sumoylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
K179 Sumoylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K181 Sumoylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K185 Sumoylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K200 Acetylation PhosphoSitePlus
K200 Sumoylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
K215 Methylation PhosphoSitePlus
K215 Sumoylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
R224 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T22 I22 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
R72 L72 Biomuta DOID:3571 / liver cancer [ icgc ]
T98 A98 Biomuta DOID:363 / uterine cancer [ tcga ]
R148 H148 Biomuta DOID:363 / uterine cancer [ tcga ]
K158 N158 Biomuta DOID:3070 / malignant glioma [ tcga ]
K215 R215 Biomuta DOID:1115 / sarcoma [ tcga ]
R224 H224 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]