Protein Information

Cytoscape View


UniProt AC / UniProt ID P0CG12 / DERPC_HUMAN
Protein Name Decreased expression in renal and prostate cancer protein
Gene Name Name: DERPC
Organism Homo sapiens (Human)

PRO ID PR:P0CG12
DAG View
PRO Name decreased expression in renal and prostate cancer protein (human)
Definition A decreased expression in renal and prostate cancer protein that is encoded in the genome of human.
Short Label hDERPC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P0CG12 (DERPC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
R5 Methylation PhosphoSitePlus
R9 Methylation PhosphoSitePlus
R11 Methylation PhosphoSitePlus
R17 Methylation PhosphoSitePlus
R23 Methylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
R91 Methylation PhosphoSitePlus
R100 Methylation PhosphoSitePlus
R114 Methylation PhosphoSitePlus
R132 Methylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
R146 Methylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
R160 Methylation PhosphoSitePlus
R172 Methylation PhosphoSitePlus
R186 Methylation PhosphoSitePlus
R201 Methylation PhosphoSitePlus
R214 Methylation PhosphoSitePlus
R225 Methylation PhosphoSitePlus
R239 Methylation PhosphoSitePlus
R252 Methylation PhosphoSitePlus
R266 Methylation PhosphoSitePlus
R280 Methylation PhosphoSitePlus
S293 O-Glycosylation GlyGen 32938750
S302 Phosphorylation PhosphoSitePlus   UniProt 23186163
R308 Methylation PhosphoSitePlus
R322 Methylation PhosphoSitePlus
S335 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
R336 Methylation PhosphoSitePlus
R350 Methylation PhosphoSitePlus
R364 Methylation PhosphoSitePlus
S369 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
S372 O-Glycosylation GlyGen 30379171, 32938750, 31492838, ...35254053, 35132862, 29351928, 28657654
S374 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
S375 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
T377 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
S380 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
T384 O-Glycosylation GlyGen 30379171, 31492838, 29351928, ...35132862, 35254053, 28657654
R387 Methylation PhosphoSitePlus
R401 Methylation PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus   UniProt 23186163
R429 Methylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
T470 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
R494 Methylation PhosphoSitePlus
R508 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R5 W5 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R11 W11 Biomuta DOID:363 / uterine cancer [ icgc ]
R23 Q23 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S70 Y70 Biomuta DOID:363 / uterine cancer [ icgc ]
R172 G172 Biomuta DOID:1324 / lung cancer [ icgc ]
S293 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S302 N302 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S335 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S372 Y372 Biomuta DOID:363 / uterine cancer [ icgc ]
R429 K429 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T468 A468 Biomuta DOID:363 / uterine cancer [ icgc ]