iPTMnet Report for P0C2W1 (FBXO45)
Protein Information
| UniProt AC / UniProt ID | P0C2W1 / FBSP1_HUMAN |
| Protein Name | F-box/SPRY domain-containing protein 1 |
| Gene Name | Name: FBXO45 Synonyms:FBX45; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P0C2W1 |
| PRO Name | F-box/SPRY domain-containing protein 1 (human) |
| Definition | An F-box/SPRY domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hFBXO45 |
| Category | organism-gene |
DAG ViewP0C2W1 (FBXO45) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C98 | Methylation | score1 | IEDB | 31844290 | ||
| K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K239 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K64 | N64 | Biomuta | [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K147 | N147 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K239 | N239 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
