iPTMnet Report P0C0L4 C4A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P0C0L4 / CO4A_HUMAN
Protein Name	Complement C4-A precursor
Gene Name	Name: C4A Synonyms:CO4,CPAMD2;
Organism	Homo sapiens (Human)

PRO ID	PR:P0C0L4 DAG View
PRO Name	complement C4-A (human)
Definition	A complement C4-A that is encoded in the genome of human.
Short Label	hC4A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P0C0L4 (C4A) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N226	N-Glycosylation		score2	GlyGen UniProt	24530628, 32125861, 19159218, ...24190977, 23090970, 18780401, 29741879, 12754519, 29671580
	Y236	Phosphorylation		score1	PhosphoSitePlus
	S310	O-Glycosylation		score1	GlyGen	31492838
	S313	O-Glycosylation		score1	GlyGen	31492838
	S668	Phosphorylation		score1	IEDB	35494241
	K678	Acetylation		score1	PhosphoSitePlus
	N862	N-Glycosylation		score2	GlyGen UniProt	16335952, 29741879
	S918	Phosphorylation		score1	UniProt	26091039
	S1109	Phosphorylation		score0	HPRD	19562805
	T1196	Phosphorylation		score1	PhosphoSitePlus
	T1224	O-Glycosylation		score1	GlyGen	34725484
	T1244	O-Glycosylation		score2	GlyGen UniProt	34725484, 23234360
	N1328	N-Glycosylation		score2	GlyGen UniProt	16335952, 24530628, 19159218, ...32125861, 24190977, 23090970, 19139490, 18780401, 29741879, 29671580
	T1330	O-Glycosylation		score1	GlyGen	28657654
	S1341	Phosphorylation		score1	PhosphoSitePlus
	S1374	Phosphorylation		score1	PhosphoSitePlus
	N1391	N-Glycosylation		score2	GlyGen UniProt	16335952, 19159218, 32125861, ...23090970, 14760718, 29741879, 29671580
	T1439	O-Glycosylation		score1	GlyGen	30459171

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N226	N-Glycosylation		score1	PRO	29741879, 29671580
	N1328	N-Glycosylation		score1	PRO	29671580
	S1341	Phosphorylation		score0	HPRD	19664994

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T1196	M1196	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc, tcga ]