iPTMnet Report for P09914 (IFIT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09914 / IFIT1_HUMAN
Protein Name Interferon-induced protein with tetratricopeptide repeats 1
Gene Name Name: IFIT1
Synonyms:G10P1,IFI56,IFNAI1,ISG56;
Organism Homo sapiens (Human)

PRO ID PR:P09914
DAG View
PRO Name interferon-induced protein with tetratricopeptide repeats 1 (human)
Definition An interferon-induced protein with tetratricopeptide repeats 1 that is encoded in the genome of human.
Short Label hIFIT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09914 (IFIT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K65 Ubiquitination PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
Y402 Phosphorylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S412 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K161 N161 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K166 M166 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K392 E392 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K392 N392 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K393 I393 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K423 N423 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]