iPTMnet Report for P09913 (IFIT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09913 / IFIT2_HUMAN
Protein Name Interferon-induced protein with tetratricopeptide repeats 2
Gene Name Name: IFIT2
Synonyms:CIG-42,G10P2,IFI54,ISG54;
Organism Homo sapiens (Human)

PRO ID PR:P09913
DAG View
PRO Name interferon-induced protein with tetratricopeptide repeats 2 (human)
Definition An interferon-induced protein with tetratricopeptide repeats 2 that is encoded in the genome of human.
Short Label hIFIT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09913 (IFIT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K309 Methylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
T366 O-Glycosylation GlyGen 30379171, 29237092
K370 Ubiquitination PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K417 Acetylation PhosphoSitePlus
K420 Acetylation PhosphoSitePlus
S424 Phosphorylation HPRD   PhosphoSitePlus 17081983
K425 Ubiquitination PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 I2 Biomuta DOID:4159 / skin cancer [ cosmic ]
K6 N6 Biomuta DOID:363 / uterine cancer [ cosmic ]
K64 N64 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K163 * Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
K221 Q221 Biomuta DOID:1324 / lung cancer [ cosmic ]
K221 E221 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K234 R234 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K417 T417 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K445 R445 Biomuta DOID:2531 / hematologic cancer [ cosmic ]