Protein Information

Cytoscape View

UniProt AC / UniProt ID P09871 / C1S_HUMAN
Protein Name Complement C1s subcomponent precursor
Gene Name Name: C1S
Organism Homo sapiens (Human)

PRO ID PR:P09871
DAG View
PRO Name complement C1s subcomponent (human)
Definition A complement C1s subcomponent that is encoded in the genome of human.
Short Label hC1S
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P09871 (C1S) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N174 N-Glycosylation UniProt 19159218, 2141278
N406 N-Glycosylation UniProt 16335952, 12788922, 19159218
S442 Phosphorylation PhosphoSitePlus
Y486 Phosphorylation PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
Y648 Phosphorylation PhosphoSitePlus
Y662 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N174 Y174 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:263 / kidney cancer [ cosmic, tcga ] DOID:2531 / hematologic cancer [ tcga ] DOID:3070 / malignant glioma [ tcga ]