Protein Information

Cytoscape View


UniProt AC / UniProt ID P09848 / LPH_HUMAN
Protein Name Lactase-phlorizin hydrolase precursor
Gene Name Name: LCT
Synonyms:LPH;
Organism Homo sapiens (Human)

PRO ID PR:P09848
DAG View
PRO Name lactase-phlorizin hydrolase (human)
Definition A lactase-phlorizin hydrolase that is encoded in the genome of human.
Short Label hLCT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09848 (LCT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S321 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S828 Phosphorylation PhosphoSitePlus
T830 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
Y836 Phosphorylation PhosphoSitePlus
T839 Phosphorylation PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
Y1068 Phosphorylation PhosphoSitePlus
S1150 Phosphorylation PhosphoSitePlus
Y1164 Phosphorylation PhosphoSitePlus
T1167 Phosphorylation PhosphoSitePlus
Y1303 Phosphorylation PhosphoSitePlus
Y1313 Phosphorylation PhosphoSitePlus
T1664 Phosphorylation PhosphoSitePlus
S1666 Phosphorylation PhosphoSitePlus
S1708 Phosphorylation PhosphoSitePlus
T1725 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S321 N321 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T839 N839 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ] DOID:3571 / liver cancer [ icgc ]
S1150 F1150 Biomuta DOID:1909 / melanoma [ icgc, tcga ]