iPTMnet Report for P09668 (CTSH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09668 / CATH_HUMAN
Protein Name Pro-cathepsin H precursor
Gene Name Name: CTSH
Synonyms:CPSB;
Organism Homo sapiens (Human)

PRO ID PR:P09668
DAG View
PRO Name pro-cathepsin H (human)
Definition A cathepsin H that is encoded in the genome of human.
Short Label hCTSH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09668 (CTSH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N66 N-Glycosylation GlyGen 24190977
N69 N-Glycosylation GlyGen 24190977
N70 N-Glycosylation GlyGen 24190977
N72 N-Glycosylation GlyGen 23090970, 24190977
Y94 Phosphorylation PhosphoSitePlus
N101 N-Glycosylation GlyGen   UniProt 23090970, 3342889, 24190977
S103 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
C141 S-Nitrosylation dbSNO 25040305
T204 Phosphorylation PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
K215 Acetylation PhosphoSitePlus
N230 N-Glycosylation GlyGen   UniProt 3342889, 19159218


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N70 I70 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C141 Y141 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T204 I204 Biomuta DOID:4159 / skin cancer [ cosmic ]