iPTMnet Report for P09603 (CSF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09603 / CSF1_HUMAN
Protein Name Macrophage colony-stimulating factor 1 precursor
Gene Name Name: CSF1
Organism Homo sapiens (Human)

PRO ID PR:P09603
DAG View
PRO Name macrophage colony-stimulating factor 1 (human)
Definition A macrophage colony-stimulating factor 1 that is encoded in the genome of human.
Short Label hCSF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09603 (CSF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N154 N-Glycosylation GlyGen 23090970, 24190977
N172 N-Glycosylation GlyGen 23090970, 24190977
N173 N-Glycosylation GlyGen 24190977
T185 O-Glycosylation GlyGen 30459171
T229 O-Glycosylation GlyGen 30459171
S233 O-Glycosylation GlyGen 30459171
S256 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T257 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T266 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T266 Phosphorylation UniProt 26091039
S309 O-Glycosylation GlyGen   UniProt 8051056
S313 O-Glycosylation GlyGen 25813380
T321 O-Glycosylation GlyGen 25813380
S326 O-Glycosylation GlyGen 25813380
S332 O-Glycosylation GlyGen 25813380
S345 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
T363 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25813380, 22171320
T365 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25813380, 22171320
T376 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
T383 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T387 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S391 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S406 O-Glycosylation GlyGen 22171320
S407 O-Glycosylation GlyGen 22171320
S414 O-Glycosylation GlyGen 25813380, 22171320
S417 O-Glycosylation GlyGen 25813380, 22171320
T418 O-Glycosylation GlyGen 25813380, 22171320
S420 O-Glycosylation GlyGen 30459171, 25813380
S420 Phosphorylation PhosphoSitePlus
S426 O-Glycosylation GlyGen 30459171, 25813380, 22171320
S426 Phosphorylation PhosphoSitePlus
S428 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S430 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S431 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S433 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S445 O-Glycosylation GlyGen 25813380
T446 O-Glycosylation GlyGen 25813380
S451 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S461 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S461 Phosphorylation PhosphoSitePlus
S473 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T477 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S533 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S461 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N172 S172 Biomuta DOID:4159 / skin cancer [ cosmic ]
N173 S173 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T229 S229 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 A233 Biomuta DOID:3571 / liver cancer [ cosmic ]
S326 P326 Biomuta DOID:1612 / breast cancer [ cosmic ]
S345 L345 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S406 L406 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S420 C420 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S430 P430 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T477 N477 Biomuta DOID:9256 / colorectal cancer [ cosmic ]