Protein Information

Cytoscape View

UniProt AC / UniProt ID P09564 / CD7_HUMAN
Protein Name T-cell antigen CD7 precursor
Gene Name Name: CD7
Organism Homo sapiens (Human)

PRO ID PR:P09564
DAG View
PRO Name T-cell antigen CD7 (human)
Definition A CD7 molecule that is encoded in the genome of human.
Short Label hCD7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P09564 (CD7) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N96 N-Glycosylation GlyGen   UniProt 19159218, 19349973
K214 Methylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation HPRD   IntAct   PhosphoSitePlus 19901323, 8918688
S226 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
T232 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P09564 (CD7) Y222 P27986 (PIK3R1) unknown eFIP 8918688
Phosphorylation P09564 (CD7) Y222 P23727 (PIK3R1) unknown eFIP 8918688

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K214 N214 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S216 L216 Biomuta DOID:363 / uterine cancer [ tcga ]
S226 L226 Biomuta DOID:9256 / colorectal cancer [ tcga ]
T232 M232 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y239 * Biomuta DOID:3571 / liver cancer [ icgc ]