iPTMnet Report for P09497 (CLTB)
Protein Information
| UniProt AC / UniProt ID | P09497 / CLCB_HUMAN |
| Protein Name | Clathrin light chain B |
| Gene Name | Name: CLTB |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P09497 |
| PRO Name | clathrin light chain B (human) |
| Definition | A clathrin light chain B that is encoded in the genome of human. |
| Short Label | hCLTB |
| Category | organism-gene |
P09497 (CLTB) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S11 | Phosphorylation | score0 | RLIMS-P | 3128543 | ||
| S13 | Phosphorylation | score0 | RLIMS-P | 3128543 | ||
| Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T187 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T190 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K194 | Methylation | score1 | PhosphoSitePlus | |||
| K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K204 | Methylation | score1 | PhosphoSitePlus | |||
| K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score3 | PhosphoSitePlus Signor | 22704991 | ||
| S205 | Phosphorylation | P25098 (GRK2) | score3 | PhosphoSitePlus Signor | 22704991 | |
| K207 | Methylation | score1 | PhosphoSitePlus | |||
| K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T225 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S11 | Phosphorylation | score2 | HPRD | 2874131, 3128543 | ||
| S11 | Phosphorylation | P19784 (CSNK2A2) | score2 | HPRD | 2874131, 3128543 | |
| S11 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 3128543 | |
| S13 | Phosphorylation | score2 | HPRD | 2874131, 3128543 | ||
| S13 | Phosphorylation | P19784 (CSNK2A2) | score2 | HPRD | 2874131, 3128543 | |
| S13 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 3128543 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S11 | Phosphorylation | score2 | HPRD | 2874131, 3128543 | ||
| S11 | Phosphorylation | P19784 (CSNK2A2) | score2 | HPRD | 2874131, 3128543 | |
| S11 | Phosphorylation | P68400 (CSNK2A1) | score2 | HPRD | 2874131, 3128543 | |
| S13 | Phosphorylation | score2 | HPRD | 2874131, 3128543 | ||
| S13 | Phosphorylation | P19784 (CSNK2A2) | score2 | HPRD | 2874131, 3128543 | |
| S13 | Phosphorylation | P68400 (CSNK2A1) | score2 | HPRD | 2874131, 3128543 | |
| S157 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S157 | F157 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K184 | N184 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S205 | N205 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T225 | M225 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ] |
DAG View