iPTMnet Report for P09417 (QDPR)
Protein Information
UniProt AC / UniProt ID | P09417 / DHPR_HUMAN |
Protein Name | Dihydropteridine reductase |
Gene Name | Name: QDPR Synonyms:DHPR,SDR33C1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P09417 |
PRO Name | dihydropteridine reductase (human) |
Definition | A dihydropteridine reductase that is encoded in the genome of human. |
Short Label | hQDPR |
Category | organism-gene |
P09417 (QDPR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
R11 | Methylation | score1 | PhosphoSitePlus | |||
Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
K109 | Methylation | score1 | PhosphoSitePlus | |||
T123 | Phosphorylation | score1 | PhosphoSitePlus | |||
T133 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
T184 | Phosphorylation | score1 | PhosphoSitePlus | |||
T187 | Phosphorylation | score1 | PhosphoSitePlus | |||
S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
T203 | Phosphorylation | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 8137944 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | V2 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
A2 | S2 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S97 | F97 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] |