iPTMnet Report for P09327 (VIL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09327 / VILI_HUMAN
Protein Name Villin-1
Gene Name Name: VIL1
Synonyms:VIL;
Organism Homo sapiens (Human)

PRO ID PR:P09327
DAG View
PRO Name villin-1 (human)
Definition A villin-1 that is encoded in the genome of human.
Short Label hVIL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09327 (VIL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation P12931 (SRC) neXtProt   PhosphoSitePlus 12269817, 18482983
Y60 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 15342783, 12269817, 18482983
Y64 Phosphorylation P12931 (SRC) neXtProt   PhosphoSitePlus 12269817, 18482983
Y81 Phosphorylation P12931 (SRC) neXtProt   PhosphoSitePlus   Signor 15342783, 12269817, 18482983
K119 Acetylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
T206 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
Y256 Phosphorylation P12931 (SRC) neXtProt   PhosphoSitePlus   Signor 15342783, 12269817, 18482983
S259 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
Y286 Phosphorylation PhosphoSitePlus
Y324 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y461 Phosphorylation PhosphoSitePlus
N526 N-Glycosylation GlyGen 29741879
K529 Ubiquitination PhosphoSitePlus
Y555 Phosphorylation PhosphoSitePlus
Y604 Phosphorylation PhosphoSitePlus
T618 Phosphorylation PhosphoSitePlus
Y681 Phosphorylation PhosphoSitePlus
T693 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus
K729 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y60 Phosphorylation P12931 (SRC) HPRD 15342783
Y81 Phosphorylation P12931 (SRC) HPRD 15342783
Y256 Phosphorylation P12931 (SRC) HPRD 15342783


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 S2 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y64 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S124 F124 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S133 F133 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S261 F261 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y286 H286 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S366 F366 Biomuta DOID:4159 / skin cancer [ cosmic ]