iPTMnet Report for P09172 (DBH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09172 / DOPO_HUMAN
Protein Name Dopamine beta-hydroxylase
Gene Name Name: DBH
Organism Homo sapiens (Human)

PRO ID PR:P09172
DAG View
PRO Name dopamine beta-hydroxylase (human)
Definition A dopamine beta-hydroxylase that is encoded in the genome of human.
Short Label hDBH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09172 (DBH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N64 N-Glycosylation GlyGen   UniProt 27152332
N184 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19139490, ...27152332, 29391424
Y310 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
N344 N-Glycosylation GlyGen   UniProt 23090970, 27152332
Y353 Phosphorylation PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
N566 N-Glycosylation GlyGen   UniProt 23090970, 27152332
S587 Phosphorylation PhosphoSitePlus
T588 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N184 D184 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y310 S310 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y334 N334 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
N344 H344 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S587 F587 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T588 I588 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]