iPTMnet Report for P09104 (ENO2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09104 / ENOG_HUMAN
Protein Name Gamma-enolase
Gene Name Name: ENO2
Organism Homo sapiens (Human)

PRO ID PR:P09104
DAG View
PRO Name gamma-enolase (human)
Definition A gamma-enolase that is encoded in the genome of human.
Short Label hENO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09104 (ENO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
Y25 Phosphorylation IEDB   PhosphoSitePlus 32387766
T26 Phosphorylation PhosphoSitePlus   UniProt 20068231
S37 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
Y44 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 18083107
R50 Methylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K105 Acetylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
Y131 Phosphorylation PhosphoSitePlus
K193 Acetylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K262 Acetylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus   UniProt 23186163
T265 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K343 Acetylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y25 Phosphorylation HPRD 20068231
T26 Phosphorylation HPRD 20068231
Y44 Phosphorylation HPRD 15592455, 20068231
T265 Phosphorylation HPRD 18510355


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 Q5 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T26 I26 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S40 F40 Biomuta DOID:4159 / skin cancer [ cosmic ]
R50 M50 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K256 R256 Biomuta DOID:2531 / hematologic cancer [ cosmic ]