iPTMnet Report for P09086 (POU2F2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09086 / PO2F2_HUMAN
Protein Name POU domain, class 2, transcription factor 2
Gene Name Name: POU2F2
Synonyms:OCT2,OTF2;
Organism Homo sapiens (Human)

PRO ID PR:P09086
DAG View
PRO Name POU domain, class 2, transcription factor 2 (human)
Definition A POU domain, class 2, transcription factor 2 that is encoded in the genome of human.
Short Label hPOU2F2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09086 (POU2F2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S192 O-Glycosylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S272 O-Glycosylation PhosphoSitePlus
S275 O-Glycosylation PhosphoSitePlus
T302 O-Glycosylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
R309 Methylation PhosphoSitePlus
S324 O-Glycosylation PhosphoSitePlus
S372 O-Glycosylation PhosphoSitePlus
S390 O-Glycosylation PhosphoSitePlus
S395 O-Glycosylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S234 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 F4 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S272 Y272 Biomuta DOID:1319 / brain cancer [ icgc ]
R309 C309 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R309 H309 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S324 * Biomuta DOID:4159 / skin cancer [ cosmic ]