Protein Information

Cytoscape View


UniProt AC / UniProt ID P09016 / HXD4_HUMAN
Protein Name Homeobox protein Hox-D4
Gene Name Name: HOXD4
Synonyms:HOX4B;
Organism Homo sapiens (Human)

PRO ID PR:P09016
DAG View
PRO Name homeobox protein Hox-D4 (human)
Definition A homeobox protein Hox-D4 that is encoded in the genome of human.
Short Label hHOXD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09016 (HOXD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S123 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
R177 Methylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S123 F123 Biomuta DOID:1324 / lung cancer [ cosmic ]
S123 P123 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T125 M125 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T125 K125 Biomuta DOID:1324 / lung cancer [ cosmic ]
R177 S177 Biomuta DOID:1781 / thyroid cancer [ icgc ]