iPTMnet Report for P09001 (MRPL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09001 / RM03_HUMAN
Protein Name Large ribosomal subunit protein uL3m precursor
Gene Name Name: MRPL3
Synonyms:MRL3,RPML3;
Organism Homo sapiens (Human)

PRO ID PR:P09001
DAG View
PRO Name 39S ribosomal protein L3, mitochondrial (human)
Definition A 39S ribosomal protein L3, mitochondrial that is encoded in the genome of human.
Short Label hMRPL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09001 (MRPL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K62 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
T111 Phosphorylation HPRD   PhosphoSitePlus 20068231
K112 Ubiquitination PhosphoSitePlus
C127 Methylation IEDB 31844290
K150 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K62 M62 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K70 E70 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S153 L153 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y265 C265 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]