iPTMnet Report for P08913 (ADRA2A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08913 / ADA2A_HUMAN
Protein Name Alpha-2A adrenergic receptor
Gene Name Name: ADRA2A
Synonyms:ADRA2R,ADRAR;
Organism Homo sapiens (Human)

PRO ID PR:P08913
DAG View
PRO Name alpha-2A adrenergic receptor (human)
Definition An alpha-2A adrenergic receptor that is encoded in the genome of human.
Short Label hADRA2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08913 (ADRA2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y147 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation IEDB 35494241
S186 Phosphorylation PhosphoSitePlus
K190 Acetylation PhosphoSitePlus
S247 Phosphorylation HPRD   PhosphoSitePlus 11732925
S247 Phosphorylation Q05655 (PRKCD) HPRD 11732925
T261 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S311 Phosphorylation HPRD   PhosphoSitePlus 7876239
S311 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 7876239
S312 Phosphorylation HPRD   PhosphoSitePlus 7876239
S312 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 7876239
S313 Phosphorylation HPRD   PhosphoSitePlus 7876239
S313 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 7876239
S314 Phosphorylation HPRD   PhosphoSitePlus 19651622, 7876239
S314 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD 19651622, 7876239
S339 Phosphorylation HPRD   PhosphoSitePlus 19651622
S346 Phosphorylation HPRD   PhosphoSitePlus 19651622
T359 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation IEDB 35494241


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S149 P149 Biomuta DOID:363 / uterine cancer [ cosmic ]
S186 F186 Biomuta DOID:4159 / skin cancer [ cosmic ]
S375 P375 Biomuta DOID:9256 / colorectal cancer [ cosmic ]