iPTMnet Report for P08908 (HTR1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08908 / 5HT1A_HUMAN
Protein Name 5-hydroxytryptamine receptor 1A
Gene Name Name: HTR1A
Synonyms:ADRB2RL1,ADRBRL1;
Organism Homo sapiens (Human)

PRO ID PR:P08908
DAG View
PRO Name 5-hydroxytryptamine receptor 1A (human)
Definition A 5-hydroxytryptamine receptor 1A that is encoded in the genome of human.
Short Label hHTR1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08908 (HTR1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T196 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
T236 O-Glycosylation GlyGen 31492838
T240 O-Glycosylation GlyGen 31492838
T240 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y215 H215 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T236 I236 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T240 P240 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K334 R334 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K334 N334 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]